Polyhexamethylene biguanide

Polyhexamethylene biguanide (CAS 32289-58-0), commonly known as PHMB or polyhexanide, is a polymeric antimicrobial agent used across industrial, healthcare, and consumer applications. It functions as a broad-spectrum biocide and preservative, effective against bacteria, fungi, and certain viruses at low use concentrations. Poly(hexamethylenebiguanide) hydrochloride is the most commercially distributed salt form.

In wound care and medical device manufacturing, polyhexanide is the active ingredient in antiseptic irrigations, wound dressings, and contact lens solutions. These applications rely on its high efficacy. Personal care formulators incorporate PHMB as a preservative in rinse-off and leave-on products including shampoos, wipes, and skin cleansers. It ensures product stability and consumer safety during use.

Textile and leather processors apply it to impart durable antimicrobial protection to fabrics, nonwovens, and treated surfaces. This prevents odor and degradation caused by microbial growth in materials. Water treatment operations use PHMB to control microbial growth in swimming pools, cooling towers, and industrial process water. It serves as a stable and effective alternative to chlorine-based biocides.

Polyhexamethylene biguanide is supplied as an aqueous solution, typically at 20% active concentration. Grades include technical, cosmetic, and pharmaceutical quality for various industrial requirements. Buyers should confirm active content, molecular weight distribution, and regulatory compliance when sourcing. This includes checking biocidal product regulations and cosmetic approvals for regulated end uses.