Polyhexamethylene biguanide

CAS Number
32289-58-0
EC Number
608-723-9
Abbreviation
PHMB

What is Polyhexamethylene biguanide?

Polyhexamethylene biguanide (CAS 32289-58-0), commonly known as PHMB or polyhexanide, is a polymeric antimicrobial agent. Poly(hexamethylenebiguanide) hydrochloride is the most commercially distributed salt form.

Where is Polyhexamethylene biguanide used?

  • Healthcare: active ingredient in antiseptic irrigations, wound dressings and contact lens solutions
  • Personal care: preservative in shampoos, wipes and skin cleansers
  • Textile and leather: durable antimicrobial protection for fabrics, nonwovens and treated surfaces
  • Water treatment: microbial control in swimming pools, cooling towers and industrial process water
  • It functions as a broad-spectrum biocide and preservative effective against bacteria, fungi and certain viruses at low use concentrations.

Good to know: Buyers should confirm active content, molecular weight distribution and regulatory compliance, including biocidal product regulations and cosmetic approvals for regulated end uses.

Commercial specifications

  • Aqueous solution, typically 20% active concentration

Other Names (Synonyms)

N'-[6-[(n'-methylcarbamimidoyl)amino]hexyl]ethanimidamide|Poly(hexamethylenebiguanide) hydrochloride|Polyhexanide|PHMB

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What are the physical properties of Polyhexamethylene biguanide?

Color White to off-white
Form Solid

How is Polyhexamethylene biguanide classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS08· Health Hazard GHS09· Environmental Hazard GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H317 May cause an allergic skin reaction
H318 Causes serious eye damage
H330 Fatal if inhaled

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
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