Chlorhexidine gluconate

Chlorhexidine gluconate (CAS 18472-51-0), abbreviated CHG and also known as chlorhexidine digluconate, is a broad-spectrum antimicrobial agent used in pharmaceutical and personal care manufacturing.

Where is Chlorhexidine gluconate used?

• Healthcare: active ingredient in surgical scrubs, pre-operative skin preparation and wound care
• Oral care: prescription-strength mouth rinses, binding to oral mucosa for prolonged action against plaque-forming bacteria
• Personal care: hand sanitizers, intimate hygiene products and medicated cleansers
• Ophthalmic solutions and contact lens care products: preservative at low concentrations
• It delivers sustained bactericidal and antifungal activity in antiseptic and preservative formulations.

Commercial specifications

• Aqueous solution, most commonly 20% and 5% concentrations
• Pharmaceutical grade to USP, BP and Ph. Eur. specifications
• Bulk supply; solution concentration is a key procurement parameter
• Grade specification is a critical factor for buyers