Ethyl 2-aminothiazole-4-carboxylate

Ethyl 2-aminothiazole-4-carboxylate (CAS 5398-36-7) is a thiazole-based building block used primarily as a pharmaceutical intermediate in the synthesis of active pharmaceutical ingredients.

Where is Ethyl 2-aminothiazole-4-carboxylate used?

• Pharmaceutical manufacturing: key intermediate in the synthesis of cephalosporin antibiotics and related beta-lactam compounds, where the aminothiazole moiety is a structurally critical fragment
• Medicinal chemistry: construction of heterocyclic libraries for drug discovery, particularly in campaigns targeting antimicrobial and antifungal candidates
• Contract manufacturing and API production: building block for regulated synthesis workflows requiring documented purity and traceability
• Specialty chemical formulators evaluate it within heterocyclic compound programs for fine chemical and agrochemical research.

Commercial specifications

• Purity specifications commonly offered include 97–99%+ grades suited to pharmaceutical intermediate and synthesis applications
• Research quantities through to multi-kilogram commercial lots