1H-Tetrazole
CAS Number
288-94-8
EC Number
206-023-4
Industries: Pharma & Healthcare
What is 1H-Tetrazole?
1H-Tetrazole (CAS 288-94-8), also referred to as 1,2,3,4-tetrazole, is a nitrogen-rich heterocyclic building block used in pharmaceutical synthesis, agrochemical development, and specialty chemical manufacturing.
Where is 1H-Tetrazole used?
- Pharmaceutical development: carboxylic acid bioisostere for modifying drug candidates
- Agrochemicals: synthetic intermediate in fungicides and herbicides
- Polymer chemistry: photoactivatable crosslinkers and polymerization initiators for specialty polymers and photoresist materials
- Biotechnology: coupling reagent in oligonucleotide synthesis, activating phosphoramidite monomers during automated DNA/RNA assembly.
Commercial specifications
- High-purity lots ≥98–99%
- Packaging from gram-scale to kilogram batches
Other Names (Synonyms)
1,2,3,4-tetrazole|D34J7PAT68|RefChem:79967|2H-Tetrazole|2,3,4-Triazapyrrole|PROVICHEM 083
What are the physical properties of 1H-Tetrazole?
Melting Point 157 °C
Boiling Point 220°C
Density 1.65 g/cm³
Flash Point 5 °C
Appearance white crystals or crystalline powder
Color Cream to orange
Form Liquid
Water Solubility Soluble
Refractive Index n 20/D 1.348
How is 1H-Tetrazole classified and handled safely? Learn More
Danger
GHS01· Explosive GHS03· Oxidizing GHS07· Irritant
Hazard Statements
H201 Explosive; mass explosion hazard
H272 May intensify fire; oxidizer
H315 Causes skin irritation
H319 Causes serious eye irritation
Precautionary Statements
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P220 Keep away from clothing and other combustible materials.
P230 Keep wetted with…
P240 Ground and bond container and receiving equipment.
Which trade and regulatory codes apply to 1H-Tetrazole?
HS Code 29339900
UN Number 1993
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 3