Azilsartan

Azilsartan (CAS 147403-03-0), also referenced under the development code TAK-536, is an angiotensin II receptor blocker (ARB) active pharmaceutical ingredient used in the treatment of hypertension.

It serves as the free acid form of the prodrug azilsartan medoxomil, and its role in the pharmaceutical supply chain centers on API manufacturing and finished dosage form development.

Azilsartan is primarily sourced by pharmaceutical manufacturers producing antihypertensive tablet formulations, where it functions as the core active ingredient for various therapeutic applications.

Contract development and manufacturing organizations (CDMOs) use it as a reference standard or synthetic intermediate when developing generic equivalents of branded ARB products.

Regulatory submissions for generic antihypertensive drugs require characterized API material, making azilsartan relevant to analytical and QA workflows for global compliance.

Research institutions also procure it for pharmacological studies comparing ARB receptor selectivity and binding profiles to better understand the mechanism of action in patients.

Azilsartan is supplied as a white to off-white crystalline powder. It is available in pharmaceutical-grade quality aligned with in-house or customer-specified specifications for manufacturing.

The material is typically offered at research, pilot, and commercial scale to support different stages of drug development and large-scale production requirements for the industry.