Dabigatran
CAS Number
211914-51-1
What is Dabigatran?
Dabigatran (CAS 211914-51-1), also referenced under the development code BIBR-953, is a direct thrombin inhibitor used as an active pharmaceutical ingredient in anticoagulant drug development.
Where is Dabigatran used?
- Oral anticoagulant formulations: pharmacologically active moiety targeting thromboembolic conditions
- Finished dosage form development for stroke prevention and venous thromboembolism treatment, typically formulated as the etexilate prodrug salt for oral bioavailability
- Reference standard or synthetic intermediate in API characterization, method validation, and quality control workflows
- Pharmacokinetic studies in research institutions and contract development organizations
- It serves as a benchmark compound in assay development for thrombin inhibition screening programs.
Commercial specifications
- Purity grades aligned with reference standard requirements
- Packaging from milligram quantities for laboratory use to larger quantities supporting API development pipelines
Other Names (Synonyms)
Pradaxa|BIBR-953|Pradaxa (dabigatran)|BIBR 953 ZW|I0VM4M70GC
What are the physical properties of Dabigatran?
Melting Point 276-277 °C
Boiling Point 797.1±70.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
Color White to Brown
Form Solid
How is Dabigatran classified and handled safely? Learn More
Warning
GHS07· Irritant
Hazard Statements
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
Which trade and regulatory codes apply to Dabigatran?
Storage Class 11 - Combustible Solids
WGK (Germany) 3