SoleChem

Dabigatran

CAS
211914-51-1
Mol. Weight
471.5 g/mol

Description

Dabigatran (CAS 211914-51-1), also referenced under the development code BIBR-953, is a direct thrombin inhibitor used as an active pharmaceutical ingredient in anticoagulant drug development. It functions as the pharmacologically active moiety in oral anticoagulant formulations targeting thromboembolic conditions.

Dabigatran is the active ingredient in finished dosage form development for stroke prevention and venous thromboembolism treatment, typically formulated as the etexilate prodrug salt for oral bioavailability.

Pharmaceutical manufacturers source it as a reference standard or synthetic intermediate during API characterization, method validation, and quality control workflows. Research institutions and contract development organizations use it in pharmacokinetic studies.

It also serves as a benchmark compound in assay development for thrombin inhibition screening programs. Supplied as a solid powder, it is available in research-grade and pharmaceutical-grade specifications suited to analytical and development applications.

Purity grades aligned with reference standard requirements are the most commonly sourced forms in the B2B market. Packaging ranges from milligram quantities for laboratory use to larger quantities supporting API development pipelines.

Our supply chain ensures that the material meets rigorous internal quality benchmarks. This product is intended for laboratory research and pharmaceutical manufacturing purposes only, ensuring consistency across various batch requirements.

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Physical Properties

Melting Point 276-277 °C
Boiling Point 797.1±70.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
Color White to Brown
Form Solid

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

Pradaxa|BIBR-953|Pradaxa (dabigatran)|BIBR 953 ZW|I0VM4M70GC

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