Dabigatran

CAS Number
211914-51-1
Chemical Formula
C25H25N7O3
Molecular Weight
471.5 g/mol

Description

Dabigatran (CAS 211914-51-1), also referenced under the development code BIBR-953, is a direct thrombin inhibitor used as an active pharmaceutical ingredient in anticoagulant drug development. It functions as the pharmacologically active moiety in oral anticoagulant formulations targeting thromboembolic conditions. Dabigatran is the active ingredient in finished dosage form development for stroke prevention and venous thromboembolism treatment, typically formulated as the etexilate prodrug salt for oral bioavailability.

Pharmaceutical manufacturers source it as a reference standard or synthetic intermediate during API characterization, method validation, and quality control workflows. Research institutions and contract development organizations use it in pharmacokinetic studies. It also serves as a benchmark compound in assay development for thrombin inhibition screening programs. Supplied as a solid powder, it is available in research-grade and pharmaceutical-grade specifications suited to analytical and development applications.

Purity grades aligned with reference standard requirements are the most commonly sourced forms in the B2B market. Packaging ranges from milligram quantities for laboratory use to larger quantities supporting API development pipelines. Our supply chain ensures that the material meets rigorous internal quality benchmarks. This product is intended for laboratory research and pharmaceutical manufacturing purposes only, ensuring consistency across various batch requirements.

Other Names (Synonyms)

Pradaxa|BIBR-953|Pradaxa (dabigatran)|BIBR 953 ZW|I0VM4M70GC

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 276-277 °C
Boiling Point 797.1±70.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
Color White to Brown
Form Solid

Documentation

Safety & Handling Learn More

Warning
GHS07· Irritant

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Trade & Regulatory

Storage Class 11 - Combustible Solids
WGK (Germany) 3
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