Ibuprofen

Ibuprofen (CAS 15687-27-1) is a non-steroidal anti-inflammatory active pharmaceutical ingredient used across prescription and OTC drug manufacturing globally. Sourced in bulk API form, it functions as the primary analgesic agent. The largest commercial demand comes from OTC tablet and capsule production, where it is the active ingredient in pain relief and fever reduction products. Liquid suspension manufacturing represents a distinct high-volume segment.

These pediatric formulations require specific particle size and solubility profiles to ensure efficacy. Topical pharmaceutical products, including gels and creams for localized pain, rely on defined concentrations for transdermal delivery. Contract manufacturers and generic drug producers also source this material as a starting material or intermediate. It is frequently used in the synthesis of ibuprofen lysinate and other specialized salt-form derivatives.

The product is supplied as a white crystalline powder in bulk quantities, typically ranging from kilogram to multi-tonne lots. Standard grades include USP, BP, Ph.Eur., and JP for global compliance. Grade selection is driven by the target market's regulatory requirements and specific formulation needs. Micronized grades are available for applications where enhanced dissolution rate or suspension uniformity is a priority.