Ibuprofen

Ibuprofen (CAS 15687-27-1) is a non-steroidal anti-inflammatory active pharmaceutical ingredient used in prescription and OTC drug manufacturing.

Where is Ibuprofen used?

• OTC tablets and capsules: active ingredient in pain relief and fever reduction
• Liquid suspensions: high-volume pediatric formulations
• Topical gels and creams: localized pain relief via transdermal delivery
• Contract manufacturers and generic drug producers source it as a starting material or intermediate
• It is frequently used in the synthesis of ibuprofen lysinate and other salt-form derivatives.

Good to know: Pediatric formulations require specific particle size and solubility profiles. Micronized grades are available where enhanced dissolution rate or suspension uniformity is a priority.

Commercial specifications

• Standard grades include USP, BP, Ph. Eur., and JP
• Grade selection driven by target market regulatory requirements and formulation needs