Dibenzoyl-L-tartaric acid monohydrate
What is Dibenzoyl-L-tartaric acid monohydrate?
Dibenzoyl-L-tartaric acid monohydrate (CAS 62708-56-9), abbreviated L-DBTA, is a chiral resolving agent derived from L-tartaric acid.
Where is Dibenzoyl-L-tartaric acid monohydrate used?
- Pharmaceutical manufacturing: separation of racemic mixtures via diastereomeric salt formation
- Resolution of chiral amines, amino acids and alkaloid-type APIs
- API synthesis: isolation of target enantiomers at pilot and commercial scale
- Biotechnology: production of chiral building blocks for peptide drug candidates
- Specialty chemicals: chiral catalyst precursor in asymmetric synthesis workflows
- It also resolves small-molecule drug candidates during development.
Good to know: Separation occurs through diastereomeric salt formation, allowing isolation of enantiomerically pure compounds; this avoids the cost and complexity of chiral chromatography.
Commercial specifications
- Laboratory quantities through to multi-kilogram lots
Other Names (Synonyms)
(-)-O,O'-Dibenzoyl-L-tartaric acid monohydrate|RefChem:855006|O,O'-Dibenzoyl-(2R,3R)-tartaric acid monohydrate|(2R,3R)-2,3-Bis(benzoyloxy)succinic acid hydrate|Butanedioic acid, 2,3-bis(benzoyloxy)-, monohydrate, [R-(R*,R*)]-|(-)-O,O'-Dibenzoyl-L-tartaric acid hydrate|(2R,3R)-2,3-dibenzoyloxybutanedioic acid;hydrate|Butanedioic acid, 2,3-bis(benzoyloxy)-, hydrate (1:1), (2R,3R)-|L-DBTA