L-phenylalanine

CAS Number
63-91-2
EC Number
200-568-1
Chemical Formula
C9H11NO2
Molecular Weight
165.19 g/mol
FEMA Number
FEMA 3585
Abbreviation
L-Phe

Description

L-Phenylalanine (CAS 63-91-2) is an essential amino acid supplied as a pure crystalline ingredient for nutritional, pharmaceutical, and specialty formulation use. Known in the trade as L-Phe and assigned FEMA 3585, it is a critical raw material. It serves as the direct biosynthetic precursor to several high-value compounds, including aspartame, making it essential for sweetener and flavor manufacturers. In food and beverage manufacturing, it is the key building block for large-scale production.

Pharmaceutical formulators use it as an active ingredient and synthesis intermediate in amino acid infusion solutions and parenteral nutrition products. It is also utilized extensively in peptide drug manufacturing and specialized medical foods. Sports nutrition and dietary supplement brands incorporate it into free-form amino acid blends and protein fortification systems. These applications target muscle recovery and metabolic support for high-performance athletes and health-conscious consumers.

Personal care formulators apply it in skin-conditioning and antioxidant-stabilized topical products where amino acid actives are specified. It provides functional benefits in various cosmetic formulations requiring high-purity chemical inputs. L-Phenylalanine is supplied as a white crystalline powder in both food-grade and pharmaceutical-grade specifications. Recognized quality standards include USP, BP, Ph. Eur., and FCC, supporting global sourcing.

Standard pack sizes range from kilogram quantities to bulk metric-ton shipments to meet diverse industrial needs. Fermentation-derived material is available to meet clean-label and non-GMO positioning requirements for modern brands.

Other Names (Synonyms)

Phe|3-phenyl-L-alanine|β-phenyl-L-alanine|L-Phe|beta-Phenyl-L-alanine|(S)-alpha-Amino-beta-phenylpropionic acid|(S)-2-Amino-3-phenylpropionic acid|(2S)-2-azaniumyl-3-phenylpropanoate

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 283 °C (decomp)
Boiling Point 293.03°C (rough estimate)
Density 1.290 g/cm³
Appearance White crystalline powder
Color White to off-white
Odor at 100.00 %. odorless
Form powder
Water Solubility 1-5 g/100 mL at 25 ºC
Vapor Pressure <1 Pa (25 °C)
Refractive Index -34 ° (C=2, H2O)
pH 5.0-7.0 (25℃, 0.1M in H2O)
Log P 0.24

Trade & Regulatory

HS Code 29224995
Storage Class 13 - Non Combustible Solids
WGK (Germany) 3

Documentation

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