1-methylimidazole
Description
1-Methylimidazole (CAS 616-47-7), commonly abbreviated as NMI, is a nitrogen-containing heterocyclic compound used industrially as a catalyst, curing agent, and synthesis intermediate.
Its reactivity toward electrophiles and metal coordination makes it a practical building block across pharmaceutical manufacturing, polymer chemistry, and specialty coatings.
In epoxy resin systems, NMI functions as a latent curing agent and cure accelerator, enabling controlled crosslinking in electrical laminates, adhesives, and industrial coatings.
Pharmaceutical manufacturers use it as a coupling catalyst in peptide synthesis and acylation reactions, where it improves reaction efficiency and yield at scale.
NMI is a key precursor in the synthesis of ionic liquids, particularly imidazolium-based salts used as reaction media or electrolytes in battery and electrochemical applications.
It also serves as a ligand or co-catalyst in organometallic processes, supporting active pharmaceutical ingredient (API) production and fine chemical synthesis.
1-Methylimidazole is supplied as a colorless to pale yellow liquid in drums, IBCs, and bulk quantities. Technical grade is the standard commercial offering for most uses.
High-purity grades are available for pharmaceutical and electronic applications. Buyers should confirm water content and color specifications when sourcing for sensitive catalytic applications.
Physical Properties
| Melting Point | -6 °C |
| Boiling Point | 198-199 °C |
| Density | 1.035 g/cm³ (liquid) |
| Flash Point | 198 °F |
| Appearance | Clear colorless to yellow liquid |
| Color | Clear colorless to yellow |
| Form | Liquid |
| Water Solubility | Miscible with water. |
| Vapor Pressure | 0.4 mm Hg ( 20 °C) |
| Refractive Index | n 20/D 1.495(lit.) |
| pH | 9.5-10.5 (50g/l, H2O, 20℃) |
| Log P | -0.19 at 25℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29332990 |
| UN Number | 3267 |
| ADR Class | 8 |
| Packing Group | II |
| WGK (Germany) | 1 |
Documentation
Other Names
N-Methylimidazole|1-Methyl-1H-imidazole|1H-Imidazole, 1-methyl-|IMIDAZOLE, 1-METHYL-|P4617QS63Y|1-methyl-1H-imidazol-3-ium|N1-Methylimidazole|NMI
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