1,4-Pentanediamine

1,4-Pentanediamine (CAS 591-77-5), also known as 1,4-diaminopentane, is a branched-chain aliphatic diamine used as a building block in pharmaceutical synthesis and specialty chemical manufacturing.

Where is 1,4-Pentanediamine used?

• Pharmaceutical development: chiral intermediate for synthesizing active pharmaceutical ingredients
• Biotechnology: preparation of polyamine analogs and conjugates for drug delivery and nucleic acid binding studies
• Linker or spacer molecule in the construction of peptidomimetics and other bioactive scaffolds
• Specialty polymer chemistry: evaluation for producing polyamides and polyureas with modified chain geometry
• Its asymmetric structure makes it a sought-after intermediate where standard linear diamines are unsuitable.

Good to know: These applications require defined stereochemical configurations for optimal efficacy. This provides unique properties compared to standard linear diamine feedstocks.

Commercial specifications

• Purity grades commonly ranging from 95% to 98%+ for synthetic applications
• Research and development quantities through to multi-kilogram lots
• Packaging generally offered in sealed glass or HDPE containers