Disalicylalpropylenediimine

CAS Number
94-91-7
EC Number
202-374-2

What is Disalicylalpropylenediimine?

Disalicylalpropylenediimine (CAS 94-91-7), also known as N,N-disalicylidene propanediamine, is a Schiff base ligand used in pharmaceutical synthesis and catalytic chemistry.

Where is Disalicylalpropylenediimine used?

  • Pharmaceutical and biotechnology research: precursor
  • Synthesis of metal-Schiff base complexes evaluated as active intermediates in drug development pipelines
  • Copper, cobalt, and manganese complexes as catalyst precursors
  • Oxidation and asymmetric synthesis reactions with controlled selectivity
  • Coordination chemistry platforms: building salen-type ligand frameworks
  • Research-scale procurement is common for screening metal complex libraries in medicinal chemistry and enzyme-mimetic studies.

Good to know: It functions as a chelating agent that coordinates transition metals into stable complexes with defined geometry. Bulk availability varies by supplier; confirm specification documentation before committing to larger volumes.

Commercial specifications

  • Research and development quantities from gram to kilogram scale
  • Purity confirmed by HPLC or elemental analysis

Other Names (Synonyms)

Α,α'-propylenedinitrilodi-o-cresol|N,n-disalicylidene propanediamine|2-[2-[(2-hydroxyphenyl)methylideneamino]propyliminomethyl]phenol|N,n'-disalicylidene-1,2-propanediamine

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What are the physical properties of Disalicylalpropylenediimine?

Melting Point 101 °C
Boiling Point 424.95°C (rough estimate)
Density 1.0787 (rough estimate)
Color Light orange to Yellow to Green
Form powder to crystal
Water Solubility 190mg/L at 20℃
Vapor Pressure 0.001Pa at 50℃
Refractive Index 1.5750 (estimate)
Log P 3.6 at 23℃

How is Disalicylalpropylenediimine classified and handled safely? Learn More

Danger
GHS02· Flammable GHS07· Irritant GHS08· Health Hazard GHS09· Environmental Hazard

Hazard Statements

H302 Harmful if swallowed [Warning Acute toxicity, oral]
H360 May damage fertility or the unborn child [Danger Reproductive toxicity]
H371 May cause damage to organs [Warning Specific target organ toxicity, single exposure]
H401 Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard]
H412 Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Which trade and regulatory codes apply to Disalicylalpropylenediimine?

HS Code 2925.29.9000
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