SoleChem

Disalicylalpropylenediimine

CAS
94-91-7
EC
202-374-2
Mol. Weight
282.34 g/mol

Description

Disalicylalpropylenediimine (CAS 94-91-7), also known as N,N-disalicylidene propanediamine, is a Schiff base ligand used in pharmaceutical synthesis and catalytic chemistry.

It functions primarily as a chelating agent capable of coordinating transition metals to form stable metal complexes with defined geometry. In pharmaceutical and biotechnology research, it serves as a precursor.

This material is used for synthesizing metal-Schiff base complexes evaluated as active intermediates in drug development pipelines. Its copper, cobalt, and manganese complexes are employed as catalyst precursors.

These complexes are used in oxidation and asymmetric synthesis reactions, where controlled selectivity is critical. Formulators working on coordination chemistry platforms use it to build salen-type ligand frameworks.

This is a recognized structural class in homogeneous catalysis. Research-scale procurement is common for screening metal complex libraries in medicinal chemistry and enzyme-mimetic studies.

Disalicylalpropylenediimine is supplied as a solid powder, typically in research and development quantities ranging from gram to kilogram scale. Technical and reagent-grade specifications are standard.

Purity levels are commonly confirmed by HPLC or elemental analysis. Bulk availability varies by supplier, and buyers should confirm specification documentation before committing to larger volumes.

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Physical Properties

Melting Point 101 °C
Boiling Point 424.95°C (rough estimate)
Density 1.0787 (rough estimate)
Color Light orange to Yellow to Green
Form powder to crystal
Water Solubility 190mg/L at 20℃
Vapor Pressure 0.001Pa at 50℃
Refractive Index 1.5750 (estimate)
Log P 3.6 at 23℃

Safety & Handling (Learn More)

Danger GHS02 GHS07 GHS08 GHS09
Hazard Statements
H302 Harmful if swallowed [Warning Acute toxicity, oral]
H360 May damage fertility or the unborn child [Danger Reproductive toxicity]
H371 May cause damage to organs [Warning Specific target organ toxicity, single exposure]
H401 Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard]
H412 Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Trade & Regulatory

HS Code 2925.29.9000

Documentation

Other Names

Α,α'-propylenedinitrilodi-o-cresol|N,n-disalicylidene propanediamine|2-[2-[(2-hydroxyphenyl)methylideneamino]propyliminomethyl]phenol|N,n'-disalicylidene-1,2-propanediamine

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