Disalicylalpropylenediimine
Description
Disalicylalpropylenediimine (CAS 94-91-7), also known as N,N-disalicylidene propanediamine, is a Schiff base ligand used in pharmaceutical synthesis and catalytic chemistry.
It functions primarily as a chelating agent capable of coordinating transition metals to form stable metal complexes with defined geometry. In pharmaceutical and biotechnology research, it serves as a precursor.
This material is used for synthesizing metal-Schiff base complexes evaluated as active intermediates in drug development pipelines. Its copper, cobalt, and manganese complexes are employed as catalyst precursors.
These complexes are used in oxidation and asymmetric synthesis reactions, where controlled selectivity is critical. Formulators working on coordination chemistry platforms use it to build salen-type ligand frameworks.
This is a recognized structural class in homogeneous catalysis. Research-scale procurement is common for screening metal complex libraries in medicinal chemistry and enzyme-mimetic studies.
Disalicylalpropylenediimine is supplied as a solid powder, typically in research and development quantities ranging from gram to kilogram scale. Technical and reagent-grade specifications are standard.
Purity levels are commonly confirmed by HPLC or elemental analysis. Bulk availability varies by supplier, and buyers should confirm specification documentation before committing to larger volumes.
Physical Properties
| Melting Point | 101 °C |
| Boiling Point | 424.95°C (rough estimate) |
| Density | 1.0787 (rough estimate) |
| Color | Light orange to Yellow to Green |
| Form | powder to crystal |
| Water Solubility | 190mg/L at 20℃ |
| Vapor Pressure | 0.001Pa at 50℃ |
| Refractive Index | 1.5750 (estimate) |
| Log P | 3.6 at 23℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 2925.29.9000 |
Documentation
Other Names
Α,α'-propylenedinitrilodi-o-cresol|N,n-disalicylidene propanediamine|2-[2-[(2-hydroxyphenyl)methylideneamino]propyliminomethyl]phenol|N,n'-disalicylidene-1,2-propanediamine
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