Thiophene
Description
Thiophene (CAS 110-02-1), also known as thiofuran or thiole, is a sulfur-containing heterocyclic compound used as a chemical intermediate and flavoring agent in the food and fragrance industry.
It provides a characteristic sulfurous, meat-like aromatic profile that underpins a range of synthetic flavor systems. In food flavoring, thiophene derivatives are used to recreate roasted, cooked meat, and savory notes.
These compounds are essential in processed food products, seasonings, and flavor blends. It also functions as a key building block in the synthesis of more complex heterocyclic flavor compounds for the industry.
The ring structure is modified to produce targeted aroma profiles for various applications. Fragrance formulators use thiophene-based intermediates in specialty compositions requiring sulfurous or roasted character.
Beyond flavor and fragrance, it serves as a synthetic intermediate in fine chemical and pharmaceutical manufacturing. The thiophene ring is frequently incorporated into active compound structures for medicine.
Thiophene is supplied as a liquid in standard commercial packaging, with drum and bulk quantities available for industrial buyers. It is offered in technical and high-purity grades for diverse needs.
Purity levels are typically at 99% or above for flavor and fine chemical applications. Buyers should confirm grade specifications against their formulation or synthesis requirements prior to sourcing materials.
Physical Properties
| Melting Point | -39.4 °C |
| Boiling Point | 84.0 °C @ Press: 760 Torr |
| Density | 1.06494 g/cm³ @ Temp: 20 °C |
| Flash Point | -9 °C |
| Appearance | colourless to pale yellow liquid |
| Color | Clear |
| Odor | at 0.10 % in propylene glycol. alliaceous garlic |
| Form | powder |
| Water Solubility | INSOLUBLE |
| Vapor Pressure | 40 mm Hg ( 12.5 °C) |
| Refractive Index | n 20/D 1.529(lit.) |
| Log P | 1.81-1.86 at pH10 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29349990 |
| UN Number | 2414 |
| ADR Class | 3 |
| Packing Group | II |
| Storage Class | 3 - Flammable liquids |
| WGK (Germany) | 3 |
Documentation
Other Names
Thiophen|Thiole|thiofuran|Thiofuram|Thiofen|Thiaphene|Divinylene sulfide|Tetrole
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