Benzonitrile

Benzonitrile (CAS 100-47-0), also known as phenyl cyanide, is an aromatic nitrile solvent and chemical intermediate.

Where is Benzonitrile used?

• Pharmaceutical manufacturing: key intermediate in the synthesis of active pharmaceutical ingredients
• Flavor and fragrance: precursor to benzylamine derivatives and aromatic aroma compounds
• Catalyst development: ligand precursor and stabilizing agent in transition metal catalyst systems, including palladium-based catalysts
• Specialty chemicals: solvent in electrochemical applications and high-polarity reaction media
• In multi-step organic synthesis it serves as a reactive building block and polar aprotic solvent.

Good to know: Often used where conventional solvents are unsuitable for specific chemical reactions. Buyers sourcing for regulated end uses should confirm purity certificates and residual impurity profiles with suppliers.

Commercial specifications

• High-purity grades of 99% or greater for pharmaceutical and catalyst applications
• Clear liquid in laboratory quantities, bulk drums and IBC containers