SoleChem

n-ethylmorpholine

CAS
100-74-3
EC
202-885-0
Mol. Weight
115.17 g/mol

Description

N-Ethylmorpholine (CAS 100-74-3), commonly abbreviated as NEM, is a tertiary amine used as a catalyst and pH-regulating agent across specialty chemical manufacturing. It functions as a reactive intermediate and process catalyst.

This chemical serves as a solvent in systems where controlled basicity and miscibility with polar media are required. In polyurethane production, NEM acts as a blowing and gelation catalyst, influencing foam cell structure.

It is used in both flexible and rigid foam formulations to manage the cure rate effectively. Coatings and resin manufacturers use it as a neutralizing amine to stabilize waterborne systems and adjust pH levels.

The compound is particularly useful in acrylic and alkyd dispersions. Pharmaceutical synthesis relies on NEM as a non-nucleophilic base and reaction solvent in multi-step organic processes where selectivity is critical.

Mild basicity makes it an ideal choice for sensitive chemical reactions. In metalworking fluids and lubricant concentrates, it functions as a corrosion inhibitor component and an effective emulsion stabilizer.

N-Ethylmorpholine is supplied as a clear liquid, typically in drum and IBC quantities for industrial buyers. Technical grade is the standard commercial offering for most large-scale manufacturing applications.

High-purity grades are available for pharmaceutical and fine chemical applications. Specifications vary by supplier, with purity levels commonly at 99% or above for process-critical uses in various industries.

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Physical Properties

Melting Point -62.78 °C
Boiling Point 138-139 °C @ Press: 763 Torr
Density 0.8996 g/cm³ @ Temp: 20 °C
Flash Point 82 °F
Appearance 4-Ethylmorpholine is a colorless liquid with an ammonia-like odor.
Color Cream to beige to brown-grey
Form Powder
Water Solubility miscible
Vapor Pressure 8.1 hPa (20 °C)
Refractive Index n 20/D 1.441(lit.)
pH 11.8 (100g/l, H2O, 20℃)
Log P 0.08 at 24.6℃

Safety & Handling (Learn More)

Danger GHS02 GHS05 GHS06 GHS07 GHS08
Hazard Statements
H226 Flammable liquid and vapor
H302 Harmful if swallowed
H311 Toxic in contact with skin
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H315 Causes skin irritation
H316 Causes mild skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation
H320 Causes eye irritation
H331 Toxic if inhaled
H332 Harmful if inhaled
H335 May cause respiratory irritation
H361 Suspected of damaging fertility or the unborn child
H371 May cause damage to organs
H373 May causes damage to organs through prolonged or repeated exposure
H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P308+P316 Get emergency medical help immediately.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P362+P364 Take off contaminated clothing and wash it before reuse.
P370+P378 Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P301+P330+P331 Rinse mouth. Do NOT induce vomiting.
P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29349990
UN Number 2920
ADR Class 8
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1

Documentation

Other Names

4-ethylmorpholine|Morpholine, 4-ethyl-|N-Ethylmorfolin|ECM0G991FQ|NEM

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