Amines REACH

n-ethylmorpholine

CAS Number
100-74-3
EC Number
202-885-0
Chemical Formula
C6H13NO
Molecular Weight
115.17 g/mol
Abbreviation
NEM

Description

N-Ethylmorpholine (CAS 100-74-3), commonly abbreviated as NEM, is a tertiary amine used as a catalyst and pH-regulating agent across specialty chemical manufacturing. It functions as a reactive intermediate and process catalyst. This chemical serves as a solvent in systems where controlled basicity and miscibility with polar media are required. In polyurethane production, NEM acts as a blowing and gelation catalyst, influencing foam cell structure.

It is used in both flexible and rigid foam formulations to manage the cure rate effectively. Coatings and resin manufacturers use it as a neutralizing amine to stabilize waterborne systems and adjust pH levels. The compound is particularly useful in acrylic and alkyd dispersions. Pharmaceutical synthesis relies on NEM as a non-nucleophilic base and reaction solvent in multi-step organic processes where selectivity is critical.

Mild basicity makes it an ideal choice for sensitive chemical reactions. In metalworking fluids and lubricant concentrates, it functions as a corrosion inhibitor component and an effective emulsion stabilizer. N-Ethylmorpholine is supplied as a clear liquid, typically in drum and IBC quantities for industrial buyers. Technical grade is the standard commercial offering for most large-scale manufacturing applications.

High-purity grades are available for pharmaceutical and fine chemical applications. Specifications vary by supplier, with purity levels commonly at 99% or above for process-critical uses in various industries.

Other Names (Synonyms)

4-ethylmorpholine|Morpholine, 4-ethyl-|N-Ethylmorfolin|ECM0G991FQ|NEM

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -62.78 °C
Boiling Point 138-139 °C @ Press: 763 Torr
Density 0.8996 g/cm³ @ Temp: 20 °C
Flash Point 82 °F
Appearance 4-Ethylmorpholine is a colorless liquid with an ammonia-like odor.
Color Cream to beige to brown-grey
Form Powder
Water Solubility miscible
Vapor Pressure 8.1 hPa (20 °C)
Refractive Index n 20/D 1.441(lit.)
pH 11.8 (100g/l, H2O, 20℃)
Log P 0.08 at 24.6℃

Documentation

Safety & Handling Learn More

Danger
GHS02· Flammable GHS05· Corrosive GHS06· Toxic GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H226 Flammable liquid and vapor
H302 Harmful if swallowed
H311 Toxic in contact with skin
H312 Harmful in contact with skin

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.

Trade & Regulatory

HS Code 29349990
UN Number 2920
ADR Class 8
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1
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