Amines REACH

n-ethylmorpholine

CAS Number
100-74-3
EC Number
202-885-0
Abbreviation
NEM

What is n-ethylmorpholine?

N-Ethylmorpholine (CAS 100-74-3), abbreviated NEM, is a tertiary amine used as a catalyst and pH-regulating agent in specialty chemical manufacturing.

Where is n-ethylmorpholine used?

  • Reactive intermediate and process catalyst
  • Solvent where controlled basicity and miscibility with polar media are required
  • Polyurethane: blowing and gelation catalyst influencing foam cell structure in flexible and rigid foam formulations
  • Coatings and resins: neutralizing amine that stabilizes waterborne systems and adjusts pH in acrylic and alkyd dispersions
  • Pharmaceutical synthesis: non-nucleophilic base and reaction solvent in multi-step organic processes
  • Metalworking fluids and lubricant concentrates: corrosion inhibitor component and emulsion stabilizer
  • Mild basicity makes it suitable for sensitive chemical reactions.

Commercial specifications

  • Purity commonly 99% or above for process-critical uses
  • Specifications vary by supplier

Other Names (Synonyms)

4-ethylmorpholine|Morpholine, 4-ethyl-|N-Ethylmorfolin|ECM0G991FQ|NEM

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What are the physical properties of n-ethylmorpholine?

Melting Point -62.78 °C
Boiling Point 138-139 °C @ Press: 763 Torr
Density 0.8996 g/cm³ @ Temp: 20 °C
Flash Point 82 °F
Appearance 4-Ethylmorpholine is a colorless liquid with an ammonia-like odor.
Color Cream to beige to brown-grey
Form Powder
Water Solubility miscible
Vapor Pressure 8.1 hPa (20 °C)
Refractive Index n 20/D 1.441(lit.)
pH 11.8 (100g/l, H2O, 20℃)
Log P 0.08 at 24.6℃

How is n-ethylmorpholine classified and handled safely? Learn More

Danger
GHS02· Flammable GHS05· Corrosive GHS06· Toxic GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H226 Flammable liquid and vapor
H302 Harmful if swallowed
H311 Toxic in contact with skin
H312 Harmful in contact with skin

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.

Which trade and regulatory codes apply to n-ethylmorpholine?

HS Code 29349990
UN Number 2920
ADR Class 8
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1
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