Amines REACH

n-methylmorpholine n-oxide

CAS Number
7529-22-8
EC Number
231-391-8
Chemical Formula
C5H11NO2
Molecular Weight
117.15 g/mol
Abbreviation
NMO

Description

N-Methylmorpholine N-oxide (CAS 7529-22-8), commonly known as NMO, is a stable, recyclable oxidant used across chemical synthesis and industrial processing. It functions primarily as a co-oxidant in catalytic oxidation reactions. The compound also serves as a cellulose dissolution agent in fiber production. In textile and pulp manufacturing, NMO is the solvent system of choice for dissolving cellulose in the Lyocell process.

This application enables the production of fibers such as Tencel. Synthetic chemists rely on NMO as the stoichiometric co-oxidant in Sharpless dihydroxylation and Ley oxidation protocols. In these processes, it regenerates osmium tetroxide or TPAP catalysts in situ. In biotechnology and life sciences, NMO supports selective oxidation steps in the synthesis of complex molecules.

This includes the production of carbohydrates and pharmaceutical intermediates. Water treatment applications utilize NMO-based oxidation systems for degrading recalcitrant organic compounds. NMO is supplied as an aqueous solution, most commonly at 50% concentration, and as a monohydrate powder for applications requiring precise stoichiometry for chemical reactions.

Technical and reagent grades are available to serve both industrial-scale fiber processing and laboratory synthesis demands. Packaging ranges from small quantities to bulk drum supply. These options support research use as well as continuous manufacturing operations. Our product meets rigorous industry requirements for purity and performance in diverse chemical environments.

Other Names (Synonyms)

N-Methylmorpholine oxide|N-Methylmorpholine 4-oxide|4-Methylmorpholine-4-oxide|NMO|4-Methylmorpholine N-oxide|Morpholine, 4-methyl-, 4-oxide|Methyl morpholine oxide|4-Methylmorpholine Oxide

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point 120-160 °C
Boiling Point 118-119°C
Density 1,14 g/cm 3
Flash Point 118-119°C
Appearance Clear colorless to yellow solution
Color Clear colorless to yellow
Form Liquid
Water Solubility Soluble in water, methanol, ethanol, acetone, ethers and dimethylsulfoxide.
Vapor Pressure 1.41hPa at 20℃
Refractive Index n 20/D 1.43
pH 9.00 ( in neat)
Log P -1.2 at 25℃

Documentation

Safety & Handling Learn More

Danger
GHS02· Flammable GHS03· Oxidizing GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H228 Flammable solid
H272 May intensify fire; oxidizer
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H361 Suspected of damaging fertility or the unborn child

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P220 Keep away from clothing and other combustible materials.
P240 Ground and bond container and receiving equipment.

Trade & Regulatory

HS Code 29349990
Storage Class 4.1B - Flammable solid hazardous materials
WGK (Germany) 1
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