Amines
REACH
n-methylmorpholine n-oxide
CAS Number
7529-22-8
EC Number
231-391-8
Abbreviation
NMO
What is n-methylmorpholine n-oxide?
N-Methylmorpholine N-oxide (CAS 7529-22-8), commonly known as NMO, is a stable, recyclable oxidant used in chemical synthesis and industrial processing.
Where is n-methylmorpholine n-oxide used?
- Catalytic oxidation: co-oxidant
- Fiber production: cellulose dissolution agent
- Textile and pulp manufacturing: solvent system for dissolving cellulose in the Lyocell process, enabling fibers such as Tencel
- Synthetic chemistry: stoichiometric co-oxidant in Sharpless dihydroxylation and Ley oxidation protocols, regenerating osmium tetroxide or TPAP catalysts in situ
- Biotechnology and life sciences: selective oxidation steps in the synthesis of carbohydrates and pharmaceutical intermediates
- Water treatment: NMO-based oxidation systems degrade recalcitrant organic compounds.
Commercial specifications
- Aqueous solution, most commonly at 50% concentration
- Packaging from small quantities to bulk drums
Other Names (Synonyms)
N-Methylmorpholine oxide|N-Methylmorpholine 4-oxide|4-Methylmorpholine-4-oxide|NMO|4-Methylmorpholine N-oxide|Morpholine, 4-methyl-, 4-oxide|Methyl morpholine oxide|4-Methylmorpholine Oxide
What are the physical properties of n-methylmorpholine n-oxide?
Melting Point 120-160 °C
Boiling Point 118-119°C
Density 1,14 g/cm 3
Flash Point 118-119°C
Appearance Clear colorless to yellow solution
Color Clear colorless to yellow
Form Liquid
Water Solubility Soluble in water, methanol, ethanol, acetone, ethers and dimethylsulfoxide.
Vapor Pressure 1.41hPa at 20℃
Refractive Index n 20/D 1.43
pH 9.00 ( in neat)
Log P -1.2 at 25℃
How is n-methylmorpholine n-oxide classified and handled safely? Learn More
Danger
GHS02· Flammable GHS03· Oxidizing GHS07· Irritant GHS08· Health Hazard
Hazard Statements
H228 Flammable solid
H272 May intensify fire; oxidizer
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H361 Suspected of damaging fertility or the unborn child
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P220 Keep away from clothing and other combustible materials.
P240 Ground and bond container and receiving equipment.
Which trade and regulatory codes apply to n-methylmorpholine n-oxide?
HS Code 29349990
Storage Class 4.1B - Flammable solid hazardous materials
WGK (Germany) 1