n-formylmorpholine

CAS Number
4394-85-8
EC Number
224-518-3
Abbreviation
NFM

What is n-formylmorpholine?

N-Formylmorpholine (CAS 4394-85-8), abbreviated NFM, is a polar aprotic solvent.

Where is n-formylmorpholine used?

  • Pharmaceutical manufacturing: reaction solvent
  • Active ingredient synthesis: carrier where low volatility and chemical inertness are required
  • Polymer processing: dissolves and spins aromatic polyamides for fiber and membrane lines
  • Industrial cleaning: heavy-duty degreasers for resins, coatings and adhesive residues
  • Specialty chemical synthesis: controlled polarity supports high reaction yields
  • It also serves as a catalyst solvent.

Good to know: High-purity grades meet pharmaceutical and specialty chemical specifications; technical grade is standard for most industrial use. Buyers should confirm purity thresholds and water content limits against internal process requirements.

Commercial specifications

  • Intermediate packaging: drums and IBCs
  • Purity thresholds and water content limits to verify when sourcing

Other Names (Synonyms)

morpholine-4-carbaldehyde|4-morpholinecarbaldehyde|4-Formylmorpholine|4-Morpholinecarboxaldehyde|Morpholine, 4-formyl-|D1E63XO4RH|NFM

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What are the physical properties of n-formylmorpholine?

Melting Point 21 °C
Boiling Point 234-238 °C
Density 1.145 g/cm³ (liquid)
Flash Point >230 °F
Appearance CLEAR YELLOW LIQUID
Color Clear yellow
Form Liquid
Water Solubility SOLUBLE
Vapor Pressure 0.03 hPa (20 °C)
Refractive Index n 20/D 1.485(lit.)
pH 10 (250g/l, H2O, 20℃)
Log P -1.2 at 23℃

How is n-formylmorpholine classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H317 H317
H319 H319
H335 H335

Precautionary Statements

P261 P261
P271 P271
P272 P272
P280 P280

Which trade and regulatory codes apply to n-formylmorpholine?

HS Code 29349990
Storage Class 11 - Combustible Solids
WGK (Germany) 3
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