SoleChem

Morpholine

Amines Water Treatment
CAS
110-91-8
EC
203-815-1
Mol. Weight
87.12 g/mol

Description

Morpholine (CAS 110-91-8) is a cyclic amine and ether used across industrial chemistry as a corrosion inhibitor, chemical intermediate, and curing agent. Its dual amine-ether functionality makes it a building block for a broad range of downstream synthesis applications.

In steam boiler and water treatment systems, morpholine is dosed to neutralize carbonic acid and suppress corrosion in condensate return lines. It serves as a well-established alternative to volatile amines in these environments.

Pharmaceutical manufacturers use it as a synthetic intermediate in the production of active ingredients, where its secondary amine group enables targeted derivatization. This versatility is critical for complex chemical synthesis.

In rubber and polymer processing, morpholine-based accelerators and crosslinkers improve cure rates and mechanical performance in finished elastomer products. These additives are essential for high-performance industrial rubber goods.

Metalworking fluid formulators incorporate morpholine as a pH buffer and biocide component to extend fluid service life. This helps control microbial growth in demanding cutting and grinding operations across the manufacturing sector.

Morpholine is supplied as a clear liquid in standard drum, IBC, and bulk tanker quantities. Technical grade is the primary commercial form, with high-purity grades available for specialized pharmaceutical synthesis applications.

Buyers should confirm purity specifications and water content when sourcing for API intermediate use. Ensuring the material meets specific industrial requirements is vital for maintaining process stability and final product quality.

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Physical Properties

Melting Point -4.9 °C
Boiling Point 128.9 °C @ Press: 760 Torr
Density 1.0007 g/cm³ @ Temp: 20 °C
Flash Point 96 °F
Appearance Morpholine is a colorless liquid with a weak ammonia or fish-like odor. The odor threshold is 0.01 ppm.
Color APHA: ≤15
Odor Characteristic amine-like odor
Form Liquid
Water Solubility MISCIBLE
Vapor Pressure 31 mm Hg ( 38 °C)
Refractive Index n 20/D 1.454(lit.)
pH 11.2 (H2O)(undiluted)
Log P -0.860

Safety & Handling (Learn More)

Danger GHS02 GHS05 GHS07 GHS09 GHS06 GHS08
Hazard Statements
H226 Flammable liquid and vapor
H290 May be corrosive to metals
H302 Harmful if swallowed
H311 Toxic in contact with skin
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H319 Causes serious eye irritation
H331 Toxic if inhaled
H332 Harmful if inhaled
H341 Suspected of causing genetic defects
H370 Causes damage to organs
H372 Causes damage to organs through prolonged or repeated exposure
H402 Harmful to aquatic life
H411 Toxic to aquatic life with long lasting effects
H302+H312+H332 Harmful if swallowed, in contact with skin or if inhaled
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P234 Keep only in original packaging.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P316 Get emergency medical help immediately.
P317 Get emergency medical help.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P363 Wash contaminated clothing before reuse.
P390 Absorb spillage to prevent material damage.
P391 Collect spillage.
P405 Store locked up.
P406 Store in a corrosion-resistant/… container with a resistant inner liner.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P308+P316 Get emergency medical help immediately.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P361+P364 Take off immediately all contaminated clothing and wash it before reuse.
P362+P364 Take off contaminated clothing and wash it before reuse.
P370+P378 Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P301+P330+P331 Rinse mouth. Do NOT induce vomiting.
P302+P361+P354 IF ON SKIN: Take off immediately all contaminated clothing. Rinse skin with water/shower.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29349900
UN Number 2054
ADR Class 8
Packing Group I
Storage Class 3 - Flammable liquids
WGK (Germany) 3

Documentation

Other Names

tetrahydro-p-oxazine|tetrahydro-1,4-oxazine|diethylene oximide|diethylene imidoxide|1-Oxa-4-azacyclohexane|Diethylenimide oxide|Diethyleneimide oxide|Drewamine

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