Morpholine
Description
Morpholine (CAS 110-91-8) is a cyclic amine and ether used across industrial chemistry as a corrosion inhibitor, chemical intermediate, and curing agent. Its dual amine-ether functionality makes it a building block for a broad range of downstream synthesis applications.
In steam boiler and water treatment systems, morpholine is dosed to neutralize carbonic acid and suppress corrosion in condensate return lines. It serves as a well-established alternative to volatile amines in these environments.
Pharmaceutical manufacturers use it as a synthetic intermediate in the production of active ingredients, where its secondary amine group enables targeted derivatization. This versatility is critical for complex chemical synthesis.
In rubber and polymer processing, morpholine-based accelerators and crosslinkers improve cure rates and mechanical performance in finished elastomer products. These additives are essential for high-performance industrial rubber goods.
Metalworking fluid formulators incorporate morpholine as a pH buffer and biocide component to extend fluid service life. This helps control microbial growth in demanding cutting and grinding operations across the manufacturing sector.
Morpholine is supplied as a clear liquid in standard drum, IBC, and bulk tanker quantities. Technical grade is the primary commercial form, with high-purity grades available for specialized pharmaceutical synthesis applications.
Buyers should confirm purity specifications and water content when sourcing for API intermediate use. Ensuring the material meets specific industrial requirements is vital for maintaining process stability and final product quality.
Physical Properties
| Melting Point | -4.9 °C |
| Boiling Point | 128.9 °C @ Press: 760 Torr |
| Density | 1.0007 g/cm³ @ Temp: 20 °C |
| Flash Point | 96 °F |
| Appearance | Morpholine is a colorless liquid with a weak ammonia or fish-like odor. The odor threshold is 0.01 ppm. |
| Color | APHA: ≤15 |
| Odor | Characteristic amine-like odor |
| Form | Liquid |
| Water Solubility | MISCIBLE |
| Vapor Pressure | 31 mm Hg ( 38 °C) |
| Refractive Index | n 20/D 1.454(lit.) |
| pH | 11.2 (H2O)(undiluted) |
| Log P | -0.860 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29349900 |
| UN Number | 2054 |
| ADR Class | 8 |
| Packing Group | I |
| Storage Class | 3 - Flammable liquids |
| WGK (Germany) | 3 |
Documentation
Other Names
tetrahydro-p-oxazine|tetrahydro-1,4-oxazine|diethylene oximide|diethylene imidoxide|1-Oxa-4-azacyclohexane|Diethylenimide oxide|Diethyleneimide oxide|Drewamine
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