6-hydroxybenzomorpholine

CAS Number
26021-57-8
EC Number
247-415-5

What is 6-hydroxybenzomorpholine?

6-Hydroxybenzomorpholine (CAS 26021-57-8), also referenced as 3,4-Dihydro-2H-1,4-benzoxazin-6-ol, is a hydroxyl-functionalized benzoxazine heterocycle used as a building block.

Where is 6-hydroxybenzomorpholine used?

  • Pharmaceutical synthesis: key intermediate for active pharmaceutical ingredient development
  • Specialty chemical manufacturing: building block for complex molecular architectures
  • Medicinal chemistry: hydroxyl functionality enables conjugation and derivatization
  • Polymer chemistry: polymerization initiator in ring-opening systems
  • Biotechnology: preparation of probe molecules and ligand scaffolds for receptor binding studies
  • Its benzoxazine scaffold supports the construction of targeted small-molecule candidates.

Commercial specifications

  • High purity levels suited to research and intermediate-scale synthesis
  • Research quantities through to kilogram lots
  • COA, HPLC purity data, and NMR confirmation provided

Other Names (Synonyms)

3,4-Dihydro-2H-1,4-benzoxazin-6-ol|2H-1,4-Benzoxazin-6-ol, 3,4-dihydro-|77OXT3492A|3,4-DIHYDRO-2H-BENZO-(B)(1,4)OXAZIN-6-OL|3,4-DIHYDRO-6-HYDROXY-1,4(2H)-BENZOXAZINE|6-Hydroxyphenomorpholine

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What are the physical properties of 6-hydroxybenzomorpholine?

Boiling Point 334.7±42.0 °C(Predicted)
Density 1.241±0.06 g/cm3(Predicted)
Color Black
Form Solid
Water Solubility 19g/L@20°C
Vapor Pressure 0.002Pa@20°C
Log P 0.219 at 23℃

How is 6-hydroxybenzomorpholine classified and handled safely? Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H302 Harmful if swallowed
H319 Causes serious eye irritation
H411 Toxic to aquatic life with long lasting effects

Precautionary Statements

P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to 6-hydroxybenzomorpholine?

HS Code 2934999090
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