p-Cresol
Description
p-Cresol (CAS 106-44-5), also known by its FEMA 2337 designation in flavor applications, is a methylphenol derivative used across fragrance, pharmaceutical, and industrial chemistry.
It acts as a chemical building block and functional additive, serving as a precursor, preservative, and stabilizer depending on the specific formulation context and industrial requirements.
In flavors and fragrances, it contributes phenolic, smoky, and medicinal character to food flavorings and fine fragrance compositions at controlled use levels for optimal sensory profiles.
Pharmaceutical manufacturers use it as an intermediate in synthesizing antioxidants, disinfectants, and active pharmaceutical ingredients, ensuring high performance in medical applications.
In coatings and polymer systems, it functions as an antioxidant stabilizer to protect resins and elastomers from oxidative degradation during processing and throughout their service life.
Personal care formulators incorporate it at low concentrations for its preservative and antimicrobial properties in select cosmetic systems, maintaining product integrity and safety.
The product is supplied as a liquid or low-melting solid, depending on temperature conditions during handling. It is available in technical grade for industrial and coating applications.
Higher-purity grades are available for pharmaceutical intermediate and flavor use. Packaging typically ranges from drums to ISO containers for bulk procurement and global distribution.
Physical Properties
| Melting Point | 35.5 °C |
| Boiling Point | 201.8 °C |
| Density | 1.0185 g/cm³ @ Temp: 40 °C |
| Flash Point | 193 °F |
| Appearance | Cresol is a mixture of the three isomeric cresols, o-, m-, and p-cresol. Cresols are slightly soluble in water. m-Isomer: Colorless or yellow liquid with characteristic odor. |
| Color | Colorless to light yellow, may darken on exposure to light |
| Odor | at 0.10 % in dipropylene glycol. phenolic narcissus animal mimosa |
| Form | Crystalline Solid or Liquid |
| Water Solubility | 20 g/L (20 ºC) |
| Vapor Pressure | 1 mm Hg ( 20 °C) |
| Refractive Index | nD20 1.5395 |
| Log P | 1.94 |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29071200 |
| UN Number | 3455 |
| ADR Class | 6.1 |
| Packing Group | II |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| WGK (Germany) | 1 |
Documentation
Other Names
para-cresol|4-methylphenol
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