Flavors & Fragrances
REACH
p-Cresol
CAS Number
106-44-5
EC Number
203-398-6
FEMA Number
FEMA 2337
What is p-Cresol?
p-Cresol (CAS 106-44-5) is a methylphenol derivative used in fragrance, pharmaceutical, and industrial chemistry. FEMA 2337.
Where is p-Cresol used?
- Flavors and fragrances: phenolic, smoky, medicinal character in food flavorings and fine fragrance compositions
- Pharmaceuticals: intermediate in synthesizing antioxidants, disinfectants, and active pharmaceutical ingredients
- Coatings and polymer systems: antioxidant stabilizer protecting resins and elastomers from oxidative degradation
- Personal care: preservative and antimicrobial properties in select cosmetic systems
- It serves as a chemical building block and functional additive, acting as precursor, preservative, and stabilizer depending on formulation.
Commercial specifications
- Higher-purity grades for pharmaceutical intermediate and flavor use
- Packaging from drums to ISO containers
Other Names (Synonyms)
para-cresol|4-methylphenol
What are the physical properties of p-Cresol?
Melting Point 35.5 °C
Boiling Point 201.8 °C
Density 1.0185 g/cm³ @ Temp: 40 °C
Flash Point 193 °F
Appearance Cresol is a mixture of the three isomeric cresols, o-, m-, and p-cresol. Cresols are slightly soluble in water. m-Isomer: Colorless or yellow liquid with characteristic odor.
Color Colorless to light yellow, may darken on exposure to light
Odor at 0.10 % in dipropylene glycol. phenolic narcissus animal mimosa
Form Crystalline Solid or Liquid
Water Solubility 20 g/L (20 ºC)
Vapor Pressure 1 mm Hg ( 20 °C)
Refractive Index nD20 1.5395
Log P 1.94
How is p-Cresol classified and handled safely? Learn More
Danger
GHS05· Corrosive GHS06· Toxic GHS08· Health Hazard GHS07· Irritant GHS09· Environmental Hazard
Hazard Statements
H301 Toxic if swallowed
H311 Toxic in contact with skin
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P262 Do not get in eyes, on skin, or on clothing.
Which trade and regulatory codes apply to p-Cresol?
HS Code 29071200
UN Number 3455
ADR Class 6.1
Packing Group II
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
WGK (Germany) 1