Cetalkonium chloride

CAS Number
122-18-9
EC Number
204-526-3
Abbreviation
CKC

What is Cetalkonium chloride?

Cetalkonium chloride (CAS 122-18-9), also known as CKC and commercially as Banicol, is a quaternary ammonium compound. Also marketed as Banicol.

Where is Cetalkonium chloride used?

  • Pharmaceutical: preservative in ophthalmic and topical formulations, preventing microbial contamination in multi-dose products
  • Personal care: antistatic and conditioning agent in hair conditioning and rinse-off treatments
  • Textile and leather: softening and finishing agent with antimicrobial protection
  • Paper manufacturing: biocidal additive controlling microbial growth in process water and slurries
  • Its cationic character enables it to bind to negatively charged surfaces.

Good to know: Buyers should confirm purity specifications and counterion content when sourcing for pharmaceutical or personal care applications.

Commercial specifications

  • Aqueous solution, typically 25% or 50% active content

Other Names (Synonyms)

Benzyldimethylhexadecylammonium chloride|Cetyl zephiran|Banicol|Acinol|Cdbac|Zettyn|Cetyldimethylbenzylammonium chloride|Benzenemethanaminium, N-hexadecyl-N,N-dimethyl-, chloride (1:1)|CKC

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What are the physical properties of Cetalkonium chloride?

Melting Point 59 °C
Boiling Point 550.14°C (rough estimate)
Density 0.9089 (rough estimate)
Appearance white to creamy-white crystalline powder
Color White to creamy-white
Form Powder
Water Solubility MODERATELY SOLUBLE
Vapor Pressure 0Pa at 25℃
Refractive Index 1.6000 (estimate)
Log P 3.022 at 25℃

How is Cetalkonium chloride classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant GHS09· Environmental Hazard GHS08· Health Hazard GHS06· Toxic

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Cetalkonium chloride?

HS Code 29239000
UN Number 3077
ADR Class 9
Packing Group III
Storage Class 8A - Combustible corrosive hazardous materials
WGK (Germany) 3
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