SoleChem

Diisopropyl ether

Solvents Food & Nutrition
CAS
108-20-3
EC
203-560-6
Mol. Weight
102.17 g/mol

Description

Diisopropyl ether (CAS 108-20-3), also known as isopropyl ether or DIPE, is a low-polarity ether solvent used across pharmaceutical, chemical, and flavor extraction processes.

Its selective solvency and low water miscibility make it a practical choice for liquid-liquid extraction and azeotropic drying operations in various industrial settings.

In pharmaceutical and fine chemical manufacturing, DIPE is used as an extraction solvent to isolate active compounds and intermediates from aqueous reaction mixtures effectively.

Flavor and fragrance producers use it to extract and concentrate aromatic compounds from natural raw materials, where clean solvent removal is critical to end-product quality.

It also functions as a reaction solvent in organic synthesis, particularly where a low-boiling, recoverable ether is preferred over higher-residue alternatives for the process.

In fuel blending, DIPE serves as an oxygenate additive to improve octane ratings in gasoline formulations, demonstrating its versatility across different chemical sectors.

Diisopropyl ether is supplied as a liquid in drum and IBC quantities, with bulk tanker options available for large-volume industrial buyers requiring consistent supply chains.

Technical grade is the standard commercial offering, with anhydrous and stabilized variants available to meet specific handling and storage requirements for purity above 99%.

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Physical Properties

Melting Point -86.8 °C
Boiling Point 68.5 °C
Density 0.7258 g/cm³ @ Temp: 20 °C
Flash Point −29 °F
Appearance colourless liquid
Color APHA: ≤25
Odor Sweet, slightly sharp; characteristic pungent; ethereal; like amphor and ethyl ether.
Form Liquid
Water Solubility 9 g/L (20 ºC)
Vapor Pressure 120 mm Hg ( 20 °C)
Refractive Index n 20/D 1.367(lit.)
pH 7 (20°C)
Log P 2.4 at 20℃

Safety & Handling (Learn More)

Danger GHS02 GHS07 GHS08
Hazard Statements
H225 Highly Flammable liquid and vapor
H316 Causes mild skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
H336 May cause drowsiness or dizziness
H361 Suspected of damaging fertility or the unborn child
H371 May cause damage to organs
H402 Harmful to aquatic life
H412 Harmful to aquatic life with long lasting effects
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.
P242 Use non-sparking tools.
P243 Take action to prevent static discharges.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P318 IF exposed or concerned, get medical advice.
P319 Get medical advice/attention if you feel unwell.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P308+P316 Get emergency medical help immediately.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P370+P378 Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29091990
UN Number 1159
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1

Documentation

Other Names

Isopropyl ether|Diisopropyl oxide|2-Isopropoxy propane|Propane, 2,2'-oxybis-|Ether, isopropyl|Bis(isopropyl) ether|Izopropylowy eter|Ether isopropylique|DIPE

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