Diisopropyl ether

CAS Number
108-20-3
EC Number
203-560-6
Chemical Formula
C6H14O
Molecular Weight
102.17 g/mol
Abbreviation
DIPE

Description

Diisopropyl ether (CAS 108-20-3), also known as isopropyl ether or DIPE, is a low-polarity ether solvent used across pharmaceutical, chemical, and flavor extraction processes. Its selective solvency and low water miscibility make it a practical choice for liquid-liquid extraction and azeotropic drying operations in various industrial settings.

In pharmaceutical and fine chemical manufacturing, DIPE is used as an extraction solvent to isolate active compounds and intermediates from aqueous reaction mixtures effectively. Flavor and fragrance producers use it to extract and concentrate aromatic compounds from natural raw materials, where clean solvent removal is critical to end-product quality.

It also functions as a reaction solvent in organic synthesis, particularly where a low-boiling, recoverable ether is preferred over higher-residue alternatives for the process. In fuel blending, DIPE serves as an oxygenate additive to improve octane ratings in gasoline formulations, demonstrating its versatility across different chemical sectors.

Diisopropyl ether is supplied as a liquid in drum and IBC quantities, with bulk tanker options available for large-volume industrial buyers requiring consistent supply chains. Technical grade is the standard commercial offering, with anhydrous and stabilized variants available to meet specific handling and storage requirements for purity above 99%.

Other Names (Synonyms)

Isopropyl ether|Diisopropyl oxide|2-Isopropoxy propane|Propane, 2,2'-oxybis-|Ether, isopropyl|Bis(isopropyl) ether|Izopropylowy eter|Ether isopropylique|DIPE

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -86.8 °C
Boiling Point 68.5 °C
Density 0.7258 g/cm³ @ Temp: 20 °C
Flash Point −29 °F
Appearance colourless liquid
Color APHA: ≤25
Odor Sweet, slightly sharp; characteristic pungent; ethereal; like amphor and ethyl ether.
Form Liquid
Water Solubility 9 g/L (20 ºC)
Vapor Pressure 120 mm Hg ( 20 °C)
Refractive Index n 20/D 1.367(lit.)
pH 7 (20°C)
Log P 2.4 at 20℃

Documentation

Safety & Handling Learn More

Danger
GHS02· Flammable GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H225 Highly Flammable liquid and vapor
H316 Causes mild skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.

Trade & Regulatory

HS Code 29091990
UN Number 1159
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1
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