Solvents
REACH
Diisopropyl ether
CAS Number
108-20-3
EC Number
203-560-6
Abbreviation
DIPE
What is Diisopropyl ether?
Diisopropyl ether (CAS 108-20-3), also known as isopropyl ether or DIPE, is a low-polarity ether solvent.
Where is Diisopropyl ether used?
- Pharmaceutical and fine chemical manufacturing: extraction solvent to isolate active compounds and intermediates from aqueous reaction mixtures
- Flavor and fragrance production: extraction and concentration of aromatic compounds from natural raw materials
- Organic synthesis: reaction solvent where a low-boiling, recoverable ether is preferred
- Fuel blending: oxygenate additive to improve octane ratings in gasoline
- Its selective solvency and low water miscibility suit liquid-liquid extraction and azeotropic drying.
Commercial specifications
- Purity above 99%
- Anhydrous and stabilized variants
- Liquid in drums, IBCs and bulk tankers
Other Names (Synonyms)
Isopropyl ether|Diisopropyl oxide|2-Isopropoxy propane|Propane, 2,2'-oxybis-|Ether, isopropyl|Bis(isopropyl) ether|Izopropylowy eter|Ether isopropylique|DIPE
What are the physical properties of Diisopropyl ether?
Melting Point -86.8 °C
Boiling Point 68.5 °C
Density 0.7258 g/cm³ @ Temp: 20 °C
Flash Point −29 °F
Appearance colourless liquid
Color APHA: ≤25
Odor Sweet, slightly sharp; characteristic pungent; ethereal; like amphor and ethyl ether.
Form Liquid
Water Solubility 9 g/L (20 ºC)
Vapor Pressure 120 mm Hg ( 20 °C)
Refractive Index n 20/D 1.367(lit.)
pH 7 (20°C)
Log P 2.4 at 20℃
How is Diisopropyl ether classified and handled safely? Learn More
Danger
GHS02· Flammable GHS07· Irritant GHS08· Health Hazard
Hazard Statements
H225 Highly Flammable liquid and vapor
H316 Causes mild skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P203 Obtain, consult and follow expert instructions for use.
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
Which trade and regulatory codes apply to Diisopropyl ether?
HS Code 29091990
UN Number 1159
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 1