Diethylene glycol dimethyl ether
Description
Diethylene glycol dimethyl ether (CAS 111-96-6), commercially known as Diglyme, is a high-boiling aprotic ether solvent used across pharmaceutical synthesis and polymer processing.
Its controlled evaporation rate and strong solvating power make it a preferred solvent where lower-boiling alternatives fail to maintain process stability during specialty chemical manufacturing.
In pharmaceutical manufacturing, Diglyme functions as a reaction solvent for Grignard reactions, metal hydride reductions, and other moisture-sensitive syntheses requiring an inert, coordinating medium.
Polymer formulators use it as a polymerization solvent and chain-transfer agent in the production of specialty resins and adhesives for industrial applications.
In battery electrolyte research and lithium-ion cell development, it serves as a co-solvent that improves ionic conductivity and electrode compatibility for advanced energy storage.
Biotechnology applications include its use as a carrier solvent in reagent formulations where consistent solvation and low reactivity with biological substrates are required.
Diglyme is supplied as a clear liquid in drum, IBC, and bulk quantities. Technical grade is the standard offering for industrial and research applications across the global market.
Anhydrous and high-purity grades are available to meet pharmaceutical and battery-grade specifications. Packaging options typically range from laboratory-scale containers to full bulk tanker supply.
Physical Properties
| Melting Point | -68 °C |
| Boiling Point | 162 °C @ Press: 760 Torr |
| Density | 0.9451 g/cm³ @ Temp: 20 °C |
| Flash Point | 134.6 °F |
| Appearance | Colorless clear liquid |
| Color | ≤10(APHA) |
| Odor | Mild ethereal. |
| Form | Liquid |
| Water Solubility | Miscible |
| Vapor Pressure | 3 mm Hg ( 20 °C) |
| Refractive Index | n 20/D 1.408(lit.) |
| pH | 7 (20°C) |
| Log P | -0.36 at 25℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29091900 |
| UN Number | 3271 |
| ADR Class | 3 |
| Packing Group | III |
| Storage Class | 3 - Flammable liquids |
| WGK (Germany) | 1 |
Documentation
Other Names
Diethylene glycol dimethylether|1-methoxy-2-(2-methoxyethoxy)ethane|Diglyme
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