Triethylene glycol dimethyl ether

CAS Number
112-49-2
EC Number
203-977-3

What is Triethylene glycol dimethyl ether?

Triethylene glycol dimethyl ether (CAS 112-49-2), commercially known as Triglyme, is a high-boiling, aprotic ether solvent.

Where is Triethylene glycol dimethyl ether used?

  • Pharmaceutical manufacturing: reaction solvent
  • Electronics: solvent in electrolyte formulations
  • Lithium batteries: coordination chemistry with lithium ions influences cell performance
  • Oil and gas processing: extraction and absorption solvent for gas treatment
  • Metalworking and lubricants: carrier fluid in specialty formulations requiring thermal stability
  • It serves as a carrier and reaction medium where conventional solvents fall short.

Good to know: High-purity grades meet the tighter requirements of battery electrolyte and pharmaceutical synthesis applications. Buyers should confirm purity levels and water content specifications.

Commercial specifications

  • Standard packaging: drums to IBC containers and bulk quantities
  • Technical grade is the most common commercial specification
  • High-purity grades available

Other Names (Synonyms)

1-methoxy-2-[2-(2-methoxyethoxy)ethoxy]ethane|Triglyme

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What are the physical properties of Triethylene glycol dimethyl ether?

Melting Point -45 °C
Boiling Point 216 °C
Density 0.980 g/cm³
Flash Point 231 °F
Appearance Water-white liquid; mild ether odor. D 0.9862 (20/20C), refr index 1.4233 (20C), flash p 232F (111C), bp 216.0C (760mmHg), 153.6C (100 mm Hg), fp ?46C. Completely soluble in water and hydrocarbons at 20C. May contain peroxides. Combustible.
Color APHA: ≤20
Form Liquid
Water Solubility Soluble
Vapor Pressure 1.2 hPa (20 °C)
Refractive Index n 20/D 1.423(lit.)
pH 7
Log P -0.52 at 20℃

How is Triethylene glycol dimethyl ether classified and handled safely? Learn More

Danger
GHS08· Health Hazard GHS07· Irritant

Hazard Statements

H319 Causes serious eye irritation
H360 May damage fertility or the unborn child
H361 Suspected of damaging fertility or the unborn child

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P318 IF exposed or concerned, get medical advice.
P405 Store locked up.

Which trade and regulatory codes apply to Triethylene glycol dimethyl ether?

HS Code 29094990
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 1
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