Hexadecyltrimethoxysilane

CAS Number
16415-12-6
EC Number
240-464-3

What is Hexadecyltrimethoxysilane?

Hexadecyltrimethoxysilane (CAS 16415-12-6), also known as Cetyl trimethoxysilane, is a long-chain alkylsilane used to chemically modify inorganic surfaces and impart hydrophobicity.

Where is Hexadecyltrimethoxysilane used?

  • Coatings and sealants: treats mineral fillers such as silica, calcium carbonate and talc to improve dispersion and reduce moisture uptake
  • Adhesives and elastomers: coupling agent that strengthens the interface between polymer matrices and glass or silica-based reinforcements
  • Plastics compounding: surface-treated fillers deliver better mechanical performance and reduced agglomeration during processing
  • Personal care: converts powder pigments and mineral actives from hydrophilic to hydrophobic surfaces, improving skin feel and water resistance in color cosmetics
  • It bonds covalently to mineral substrates, enabling durable water repellency and improved compatibility between inorganic fillers and organic matrices.

Commercial specifications

  • Purity 95% or higher, technical grade
  • Packaging from small drums to bulk IBC containers

Other Names (Synonyms)

Silane, hexadecyltrimethoxy-|Cetyl trimethoxysilane|n-Hexadecyltrimethoxysilane|975S1VH3IB|DYNASYLAN 9116|SILANE 116|AY 43-216MC

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What are the physical properties of Hexadecyltrimethoxysilane?

Melting Point -1 °C
Boiling Point 155 °C @ Press: 0.2 Torr
Density 0.890 g/cm³
Flash Point 165°C
Color Colorless to Almost colorless
Form clear liquid
Water Solubility 2μg/L at 20℃
Vapor Pressure 0Pa at 20℃
Refractive Index n 20/D 1.44
Log P 8.1 at 20℃

How is Hexadecyltrimethoxysilane classified and handled safely? Learn More

Warning
GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to Hexadecyltrimethoxysilane?

HS Code 29319090
Storage Class 10 - Combustible liquids
WGK (Germany) 1
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