Hexamethyldisiloxane

CAS Number
107-46-0
EC Number
203-492-7
Chemical Formula
C6H18OSi2
Molecular Weight
162.38 g/mol
Abbreviation
HMDSO

Description

Hexamethyldisiloxane (CAS 107-46-0), commonly referenced as HMDSO, is a low-viscosity silicone fluid used as a solvent, carrier, and surface-modifying agent across specialty chemical manufacturing. It conditions surfaces, aids dispersion of silicone-based materials, and supports film formation in coating and personal care applications. In silicone coatings and release liners, it acts as a reactive diluent.

The material functions as a processing solvent, improving flow and substrate wetting during application. Personal care formulators use it as a lightweight carrier fluid in skin-feel emollients and dry-touch formulations. It is ideal for hair conditioning products where fast evaporation and a non-greasy finish are required. In adhesives and sealants manufacturing, it functions as a solvent for silicone polymers and as a surface primer.

The chemical promotes adhesion on low-energy substrates. Plasma-enhanced chemical vapor deposition processes use HMDSO as a precursor to deposit hydrophobic or barrier silica coatings on plastics and films. Hexamethyldisiloxane is supplied as a clear, low-viscosity liquid in drum and IBC quantities. Technical and high-purity grades are available, with purity levels typically ranging from 97% to 99%+.

Cosmetic-grade material meeting relevant purity standards is also available for personal care applications. Our supply chain ensures consistent quality and reliable delivery for industrial and laboratory requirements.

Other Names (Synonyms)

oxybis(trimethylsilane)|HMDSO|bis(trimethylsilyl) oxide|bis(trimethylsilyl) ether|((CH3)3Si)2O|Disiloxane, hexamethyl-|Fluka AG|Belsil DM 0.65

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -66 °C
Boiling Point 99.5 °C
Density 0.7638 g/cm³ @ Temp: 20 °C
Flash Point 33 °F
Appearance Colorless or yellowish transparent liquid
Color Colorless to Almost colorless
Form liquid
Water Solubility insoluble
Vapor Pressure 20 hPa (20 °C)
Refractive Index n 20/D 1.377(lit.)
Log P 5.06 at 20℃

Documentation

Safety & Handling Learn More

Danger
GHS02· Flammable GHS09· Environmental Hazard GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H225 Highly Flammable liquid and vapor
H315 Causes skin irritation
H332 Harmful if inhaled
H372 Causes damage to organs through prolonged or repeated exposure

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P233 Keep container tightly closed.
P240 Ground and bond container and receiving equipment.
P241 Use explosion-proof [electrical/ventilating/lighting/…] equipment.

Trade & Regulatory

HS Code 29310095
UN Number 1993
ADR Class 3
Packing Group II
Storage Class 3 - Flammable liquids
WGK (Germany) 3
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