Dodecamethylcyclohexasiloxane

CAS Number
540-97-6
EC Number
208-762-8

What is Dodecamethylcyclohexasiloxane?

Dodecamethylcyclohexasiloxane (CAS 540-97-6), commercially recognized as Cyclomethicone 6, is a cyclic silicone fluid.

Where is Dodecamethylcyclohexasiloxane used?

  • Personal care: volatile carrier for active ingredients and conditioning agents in skin creams, hair serums, and antiperspirants
  • Coatings and release agents: improves surface wetting and reduces friction on substrates
  • Automotive and industrial lubricants: base fluid or diluent in specialty greases and mold-release compounds
  • Adhesives and sealants: blended into silicone elastomer systems to control viscosity during processing
  • It functions as a low-viscosity carrier and surface-conditioning agent.

Good to know: Buyers should confirm cyclic siloxane content and D6 purity levels against their formulation or regulatory requirements before sourcing.

Commercial specifications

  • Clear, low-viscosity liquid in drum and IBC quantities
  • Cosmetic-grade material meets purity requirements for personal care end-use

Other Names (Synonyms)

Cyclohexasiloxane, dodecamethyl-|Cyclomethicone 6|XHK3U310BA|XIAMETER PMX-0246|RefChem:590100|Cyclohexasiloxane, 2,2,4,4,6,6,8,8,10,10,12,12-dodecamethyl-|2,2,4,4,6,6,8,8,10,10,12,12-Dodecamethylcyclohexasiloxane

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What are the physical properties of Dodecamethylcyclohexasiloxane?

Melting Point -3 °C
Boiling Point 245 °C
Density 0.9677 g/cm³ @ Temp: 420 °C
Flash Point >76°C
Color Colourless
Odor Odorless
Form liquid
Water Solubility 5.1μg/L at 23℃
Vapor Pressure 4.7Pa at 25℃
Refractive Index 1.4015
Log P 8.87 at 23.6℃

How is Dodecamethylcyclohexasiloxane classified and handled safely? Learn More

Warning

Hazard Statements

H227 Combustible liquid
H413 May cause long lasting harmful effects to aquatic life

Precautionary Statements

P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P403 Store in a well-ventilated place.
P501 Dispose of contents/container in accordance with local regulations.
P370+P378 Use … for extinction.

Which trade and regulatory codes apply to Dodecamethylcyclohexasiloxane?

HS Code 29319090
UN Number 1993
Packing Group III
Storage Class 10 - Combustible liquids
WGK (Germany) 3
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