D-Propylene glycol

D-Propylene glycol (CAS 4254-15-3), also known as E490, is the stereochemically pure (S)-enantiomer of propylene glycol, distinct from the racemic form used in most industrial applications.

Where is D-Propylene glycol used?

• Personal care: humectant, solvent and stabilizer
• Cosmetics: selected where enantiomeric purity influences sensory performance, including premium moisturizers and serums
• Pharmaceuticals: solvent and co-solvent in oral, topical and injectable preparations requiring stereochemical specifications
• Polymer and resin systems: chiral building block for cross-linking and synthesis of optically active polyesters
• Coatings and adhesives: reactive intermediate for controlled curing behaviour and chain geometry affecting film properties

Good to know: Not to be confused with the racemic form used in most industrial applications. Food-grade material carries the E number designation; pharmaceutical-grade supply conforms to USP and Ph. Eur. specifications for GMP-compliant manufacturing.

Commercial specifications

• Bulk and intermediate packaging formats
• Food-grade purity standards