D-Propylene glycol
Description
D-Propylene glycol (CAS 4254-15-3), also known as E490, is the stereochemically pure (S)-enantiomer of propylene glycol, distinct from the racemic form used in most industrial applications.
It functions as a humectant, solvent, and stabilizer across personal care, pharmaceutical, and polymer manufacturing sectors. In cosmetic formulations, it is selected where enantiomeric purity influences sensory performance.
This includes premium moisturizers and serums where regulatory positioning is critical. Pharmaceutical manufacturers use it as a solvent and co-solvent in oral, topical, and injectable preparations where stereochemical specifications are required.
In polymer and resin systems, it acts as a chiral building block for cross-linking reactions and the synthesis of optically active polyesters. Coating and adhesive formulators incorporate it as a reactive intermediate.
This allows for controlled curing behavior and specific chain geometry that affect final film properties. The product is supplied as a clear, colorless liquid in bulk and intermediate packaging formats for industrial use.
Food-grade material is available under the E number designation, meeting relevant purity standards for use in regulated applications. Pharmaceutical-grade supply conforming to USP and Ph.Eur. specifications is accessible.
These grades are suitable for GMP-compliant manufacturing environments. Our supply chain ensures consistent quality and documentation for all technical, food, and pharmaceutical applications globally.
Physical Properties
| Melting Point | -59 °C |
| Boiling Point | 91-92 °C @ Press: 14 Torr |
| Density | 1.0364 g/cm³ @ Temp: 20 °C |
| Flash Point | 225 °F |
| Appearance | Colorless to light yellow liqui |
| Color | Clear colorless |
| Form | Liquid |
| Water Solubility | soluble |
| Refractive Index | n 20/D 1.432(lit.) |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29053200 |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 1 |
Documentation
Other Names
(S)-propane-1,2-diol|(+)-1,2-Propanediol|(2S)-propane-1,2-diol|(s)-1,2-propanediol|E490
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