Docusate sodium

CAS Number
577-11-7
EC Number
209-406-4
E Number
E476
Abbreviation
DSS

What is Docusate sodium?

Docusate sodium (CAS 577-11-7), also known as DSS and approved as E480 in food applications, is an anionic surfactant used across pharmaceutical, food, and industrial sectors.

Where is Docusate sodium used?

  • Pharmaceuticals: active ingredient in stool softener laxatives and wetting agent in tablet and capsule formulations to improve drug dissolution rates
  • Food: emulsifier and dispersing aid in gelled desserts, cocoa-based mixes, and sugar confectionery
  • Textile and paper processing: penetrant and wetting agent for uniform dye uptake and fiber saturation
  • Industrial cleaning and degreasing: emulsifies oils and reduces foam in process water systems
  • It lowers surface and interfacial tension, enabling emulsification, wetting, and dispersing.

Commercial specifications

  • Liquid solution typically at 70% active content in water or ethanol

Other Names (Synonyms)

dioctyl sulfosuccinate|dioctyl sodium sulfosuccinate|Dioctyl sulfosuccinate sodium salt|Aerosol OT|Dioctyl sulfosuccinate sodium|Dioctylal|Diotilan|Disonate|DSS|E480

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What are the physical properties of Docusate sodium?

Melting Point 176 °C
Boiling Point 360 °C
Density 1.13 g/cm³ (liquid)
Appearance white solid, often supplied as an aqueous solution
Color White
Form Waxy Solid
Water Solubility 1.5 g/100 mL (25 ºC)
Vapor Pressure 0Pa at 25℃
Log P 1.998 at 20℃

How is Docusate sodium classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant GHS08· Health Hazard

Hazard Statements

H302 Harmful if swallowed
H315 Causes skin irritation
H318 Causes serious eye damage
H319 Causes serious eye irritation

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P263 Avoid contact during pregnancy and while nursing.
P264 Wash … thoroughly after handling.

Which trade and regulatory codes apply to Docusate sodium?

HS Code 29171900
Storage Class 11 - Combustible Solids
WGK (Germany) 2
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