C18-Ceramide

CAS Number
2304-81-6

What is C18-Ceramide?

C18-Ceramide (CAS 2304-81-6), also known as N-stearoyl-D-erythro-sphingosine, is a naturally occurring sphingolipid that mirrors the ceramide species found in human skin.

Where is C18-Ceramide used?

  • Cosmetic and pharmaceutical formulations: structural lipid and moisture-retention agent that reinforces the skin barrier
  • Prestige and clinical skincare: barrier-repair creams, serums and emulsions that replenish lipids
  • Restoring depleted intercellular lipids in the stratum corneum
  • Topical pharmaceuticals for dry skin conditions such as eczema and psoriasis: restore lamellar lipid structure
  • Liposomal and nanoparticle drug delivery: membrane-forming properties support encapsulation efficiency and controlled release
  • Biotechnology and life sciences: reference lipid standard and functional component in cell membrane studies
  • It reduces transepidermal water loss in clinical applications.

Commercial specifications

  • Purity typically 95% to 99%+
  • Packaging from small laboratory quantities to larger bulk formats

Other Names (Synonyms)

N-stearoyl-D-erythro-sphingosine|V3Q7C63KSS|RefChem:1080585|N-Stearoylsphingosine|N-Stearoyl-D-sphingosine|Octadecanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-|Octadecanamide, N-[2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-, (E)-D-erythro-

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What are the physical properties of C18-Ceramide?

Melting Point 88-89 °C
Boiling Point 630.97°C (rough estimate)
Density 0.9512 (rough estimate)
Appearance Off White Powder
Color White to Off-White
Form White to off-white powder.
Refractive Index 1.6630 (estimate)

Which trade and regulatory codes apply to C18-Ceramide?

HS Code 29225000
WGK (Germany) 3
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