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Palladium diacetate

Salts & Minerals Personal Care & Cosmetics
CAS
3375-31-3
EC
222-164-4
Mol. Weight
224.51 g/mol

Description

Palladium diacetate (CAS 3375-31-3), commonly abbreviated as Pd(OAc)₂, is a benchmark palladium salt used as a catalyst and catalyst precursor across synthetic chemistry and industrial manufacturing.

Its high solubility in organic solvents and straightforward activation make it the go-to entry point for generating active palladium species in situ for various chemical processes.

In pharmaceutical synthesis, Pd(OAc)₂ drives cross-coupling reactions such as Suzuki, Heck, and Buchwald-Hartwig that build the carbon-carbon and carbon-heteroatom bonds found in active ingredients.

Specialty chemical manufacturers use it to catalyze carbonylation and oxidation sequences where precise selectivity is critical to yield and purity in high-value chemical production.

In biotechnology, it supports the preparation of labeled compounds and complex intermediates requiring metal-catalyzed transformations under mild conditions to preserve sensitive molecular structures.

Surface functionalization processes in electronics and advanced materials also draw on palladium acetate as a precursor for depositing catalytic palladium layers on various substrates.

Palladium diacetate is supplied as an orange-brown crystalline powder. It is available in standard reagent and high-purity catalyst grades with palladium content typically specified by suppliers.

Material is certified to meet research and manufacturing requirements. Packaging ranges from small quantities for laboratory use to larger lots for commercial-scale synthesis applications.

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Physical Properties

Melting Point 204 °C
Appearance brown needles
Color Red-brown
Form Various Forms In Red-(Powder/Flake/Crystalline/Beads)
Water Solubility insoluble
Vapor Pressure 0.002Pa at 25℃
pH 2-3 (H2O, 20℃)(aqueous suspension)
Log P -0.17 at 20℃

Safety & Handling (Learn More)

Danger GHS05 GHS07 GHS09
Hazard Statements
H302 Harmful if swallowed
H317 May cause an allergic skin reaction
H318 Causes serious eye damage
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P391 Collect spillage.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P333+P317 Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 28439090
WGK (Germany) 2

Documentation

Other Names

Palladium(2+) diacetate|Palladium(ii) acetate|Pd(OAc)2

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