Palladium diacetate

Palladium diacetate (CAS 3375-31-3), commonly abbreviated as Pd(OAc)₂, is a benchmark palladium salt used as a catalyst and catalyst precursor in synthetic chemistry and industrial manufacturing.

Where is Palladium diacetate used?

• Pharmaceutical synthesis: cross-coupling reactions such as Suzuki, Heck, and Buchwald-Hartwig that build carbon-carbon and carbon-heteroatom bonds found in active ingredients
• Specialty chemicals: carbonylation and oxidation sequences where precise selectivity is critical to yield and purity
• Biotechnology: preparation of labeled compounds and complex intermediates requiring metal-catalyzed transformations under mild conditions
• Electronics and advanced materials: surface functionalization processes that deposit catalytic palladium layers on substrates
• Its high solubility in organic solvents and straightforward activation make it the entry point for generating active palladium species in situ.

Commercial specifications

• Palladium content typically specified by suppliers
• Standard reagent and high-purity catalyst grades
• Packaging from small laboratory quantities to larger commercial-scale lots