Bisabolol

CAS Number
515-69-5
EC Number
208-205-9
FEMA Number
FEMA 4666

What is Bisabolol?

Bisabolol (CAS 515-69-5), also known as α-Bisabolol, is a naturally derived monocyclic sesquiterpene alcohol originally sourced from German chamomile.

Where is Bisabolol used?

  • Cosmetics and pharmaceuticals: skin-conditioning agent and active carrier
  • Skincare: soothing and moisturizing agent in creams, serums and lotions for sensitive or reactive skin
  • Topical pharmaceuticals: solvent for active ingredients in wound-care products and medicated creams
  • Fragrances: fixative and mild floral base note in fine fragrances and functional perfumery
  • It also appears in after-sun products, baby care lines and anti-aging formulations.

Good to know: Natural and synthetic grades exist; natural-origin material is often certified to differentiate supply chains. Natural grades commonly carry optical purity data confirming enantiomer content.

Commercial specifications

  • Natural and synthetic commercial grades
  • High purity and efficacy for wound-care and medicated creams

Other Names (Synonyms)

alpha,4-Dimethyl-alpha-(4-methyl-3-pentenyl)-3-cyclohexene-1-methanol|6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol|36HQN158VC|5-HEPTEN-2-OL, 6-METHYL-2-(4-METHYL-3-CYCLOHEXEN-1-YL)-|GZE Skincare Oil|3-Cyclohexene-1-methanol, α,4-dimethyl-α-(4-methyl-3-penten-1-yl)-, (αR,1R)-rel-|3-Cyclohexene-1-methanol, α,4-dimethyl-α-(4-methyl-3-pentenyl)-, (R*,R*)-

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What are the physical properties of Bisabolol?

Melting Point <25 °C
Boiling Point 155-157 °C @ Press: 12 Torr
Density 0.9211 g/cm³ @ Temp: 20 °C
Flash Point 135°C
Appearance colourless to faintly yellow viscous liquid
Color Clear Colourless
Odor at 100.00 %. mild floral peppery balsamic clean
Form Liquid
Water Solubility Soluble in alcohol, natural, mineral and synthetic oils. Insoluble in water.
Refractive Index n 20/D 1.496
Log P 5.63

How is Bisabolol classified and handled safely? Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H317 May cause an allergic skin reaction
H411 Toxic to aquatic life with long lasting effects

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P272 Contaminated work clothing should not be allowed out of the workplace.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Which trade and regulatory codes apply to Bisabolol?

HS Code 29061900
WGK (Germany) 2
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