SoleChem

Disodium monofluorophosphate

CAS
10163-15-2
EC
233-433-0
Mol. Weight
143.950 g/mol

Description

Disodium monofluorophosphate (CAS 10163-15-2), commonly abbreviated as MFP, is the fluoride source of choice in oral care manufacturing. Sodium phosphorofluoridate releases fluoride ions in a controlled, stable form.

This chemical integrates cleanly into dentifrice systems without the compatibility issues associated with sodium fluoride. MFP is the active ingredient in fluoride toothpastes, where it delivers enamel remineralization activity.

It is used at regulated concentration levels, typically 0.76% in finished formulations. It is also incorporated into anti-caries mouth rinses and dental gels targeting both consumer and clinical markets.

Pharmaceutical manufacturers use it in prescription-grade fluoride preparations where precise dosing and regulatory compliance are critical. In some markets, it appears in fluoride supplement tablets.

These tablets are formulated for populations with low dietary fluoride intake. Disodium monofluorophosphate is supplied as a white crystalline powder that is easy to handle during the manufacturing process.

It is available in USP and Ph. Eur. grades to meet pharmaceutical and oral care regulatory requirements. Technical grade options are also available for specific industrial applications.

Packaging ranges from kilogram-scale bags to bulk quantities suited to large-volume toothpaste and oral care manufacturers. This ensures flexibility for both pilot-scale development and full production runs.

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Physical Properties

Melting Point 625 °C
Appearance white crystalline solid
Color white
Form Powder
Water Solubility Soluble in water. Insoluble in ethanol and ether.
Vapor Pressure 0Pa at 20℃

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H302 Harmful if swallowed
H312 Harmful in contact with skin
H315 Causes skin irritation
H319 Causes serious eye irritation
H332 Harmful if inhaled
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

UN Number 3288
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Documentation

Other Names

Sodium phosphorofluoridate|Phosphorofluoridic acid, disodium salt|disodium fluorophosphate|SODIUM MONOFLUOROPHOSPHATE|Extra-Strength Aim|C810JCZ56Q|brident|MFP

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