Diethyltoluamide

Diethyltoluamide (CAS 134-62-3), widely recognized by its abbreviation DEET, is the benchmark active ingredient in insect and arthropod repellent formulations. It acts by disrupting the olfactory receptors of insects, preventing them from locating a host. This mechanism makes it the reference standard against which other repellent actives are measured. It is the primary active in consumer and professional-grade repellent products including sprays, lotions, creams, and impregnated wipes.

Concentrations typically range from 5% to 100% depending on protection duration and target market. In military and expedition-grade formulations, high-concentration products are specified for extended field use against mosquitoes and ticks. Personal care manufacturers incorporate it into pump sprays and roll-ons sold through pharmacy and outdoor retail channels. It is also used to treat fabrics and gear in combination repellent systems for outdoor gear.

While fabric-specific actives such as permethrin are common, this material remains a versatile choice for many applications. It is supplied as a clear to pale yellow liquid in bulk and drummed quantities for industrial use. Technical-grade is the standard commercial specification, with purity levels typically at 95–99%. Some suppliers offer pharmaceutical or cosmetic-grade material to support regulated consumer product registration requirements.