Diethyl phosphite

CAS Number
762-04-9
EC Number
212-091-6
Abbreviation
DEP

What is Diethyl phosphite?

Diethyl phosphite (CAS 762-04-9), also referred to commercially as diethyl phosphonate or DEP, is a reactive organophosphorus compound used as a chemical intermediate and functional additive.

Where is Diethyl phosphite used?

  • Lubricants and metalworking fluids: extreme-pressure additive and antiwear agent that reduces metal surface degradation under high-load conditions
  • Pharmaceuticals: key intermediate in the synthesis of active pharmaceutical ingredients, particularly antiviral and antiparasitic compounds
  • Agrochemicals: precursor in the manufacture of organophosphate pesticides and herbicides
  • Polymers and plastics: flame retardant additive and stabilizer
  • It acts as a building block for synthesizing phosphorus-containing compounds.

Commercial specifications

  • Drum and IBC quantities; bulk tanker supply available
  • Technical grade standard, purity typically 98% or higher
  • Pharmaceutical-intermediate grade with controlled impurity profiles from select manufacturers

Other Names (Synonyms)

phosphorous acid diethyl ester|diethyl phosphonate|diethyl hydrogenphosphite|Phosphonic acid diethyl ester|Diethoxyphosphine oxide|Diethyl acid phosphite|Hydrogen diethyl phosphite|O,O-Diethyl phosphonate|DEP

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What are the physical properties of Diethyl phosphite?

Melting Point <25 °C
Boiling Point 50-51 °C @ Press: 2 Torr
Density 1.072 g/cm³
Flash Point 180 °F
Appearance colourless liquid
Color Colorless
Form Liquid
Water Solubility miscible (hydrolysis)
Vapor Pressure 7hPa at 20℃
Refractive Index n 20/D 1.407(lit.)
Log P -0.15

How is Diethyl phosphite classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS07· Irritant

Hazard Statements

H315 Causes skin irritation
H317 May cause an allergic skin reaction
H318 Causes serious eye damage
H319 Causes serious eye irritation
H335 May cause respiratory irritation

Precautionary Statements

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P272 Contaminated work clothing should not be allowed out of the workplace.

Which trade and regulatory codes apply to Diethyl phosphite?

HS Code 29209014
Storage Class 10 - Combustible liquids
WGK (Germany) 1
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