Aluminum zirconium trichlorohydrex gly

Aluminum zirconium trichlorohydrex gly (CAS 134375-99-8), also marketed as aluminum zirconium octachlorohydrex gly, is an aluminum-zirconium complex used as the active antiperspirant ingredient in personal care formulations.

It functions by temporarily blocking eccrine sweat glands, reducing perspiration output at the skin surface. The primary application is in antiperspirant deodorant products such as sticks, roll-ons, aerosols, and creams.

In these applications, it delivers clinically recognized sweat reduction. Formulators select it over simpler aluminum salts when enhanced efficacy and longer-duration protection are required, particularly in clinical-strength or sport-positioned products.

It is also used in prescription-adjacent antiperspirant formulations where regulatory frameworks permit higher active concentrations. The glycine complexation improves skin compatibility, making it a preferred active in sensitive-skin lines.

This ingredient is a preferred choice where tolerability is a formulation requirement. Aluminum zirconium trichlorohydrex gly is supplied as a fine white powder or as aqueous solution concentrates, depending on the process.

Standard grades conform to USP monograph specifications, with active aluminum content and zirconium-to-aluminum ratios defined as key quality parameters. Buyers should confirm the buffered or unbuffered designation.

This designation affects pH behavior in finished formulations. Ensuring the correct grade is essential for maintaining stability and performance in high-end personal care and pharmaceutical-grade antiperspirant products.