Zinc citrate

CAS Number
546-46-3
EC Number
208-901-2

What is Zinc citrate?

Zinc citrate (CAS 546-46-3) is the zinc salt of citric acid, supplying bioavailable zinc.

Where is Zinc citrate used?

  • Oral care: controls tartar formation and reduces oral bacteria in toothpastes and mouthwashes
  • Dietary supplements and functional foods: zinc source with favorable absorption characteristics compared to inorganic zinc salts
  • Pharmaceutical tablets and capsules: mineral supplement active for controlled zinc delivery
  • Personal care and cosmetics: deodorants, skin preparations for antimicrobial and astringent properties
  • Industrial applications: polymer stabilization and chelation uses
  • It functions as both a mineral source and a mild antimicrobial agent.
  • Added to shampoos and hair care products to prevent dandruff and nourish the scalp.
  • Used in cosmetics for acne treatment, skin barrier strengthening, and anti-aging products.
  • Used as a mineral supplement at low doses in infant formula and clinical nutrition.

Good to know: The trihydrate is the more common commercial grade. Standard grades include food-grade and USP/BP-compliant specifications; technical-grade material is available for industrial applications.

Formulation notes

  • Recommended daily dosage in food supplements for adults is 15-30 mg of elemental zinc.
  • Incompatible with strong oxidizing agents.
  • Incompatible with strong acids (dissolution and reaction).

Typical specification

  • Zinc content assay specification is 30.0–31.5%.
  • Loss on drying specification is ≤2.0%.
  • Heavy metals specification (as Pb) is ≤10 ppm.
  • The anhydrous powder grade is supplied with approximately 31% zinc by weight.

Regulatory status

  • Listed in Directive 2002/46/EC on food supplements as a vitamin and mineral that may be used in the manufacture of food supplements.
  • Listed as a mineral salt in EU Regulation (EC) No 609/2013 on foods for infants and young children, foods for special medical purposes and total diet replacement for weight control.

Storage, packaging and handling

  • Should be stored cool (15–25°C), dry, and in a well-ventilated area.
  • Commonly supplied in polyethylene lined paper bags with 25 kg net weight.

Frequently asked questions about Zinc citrate

What form is zinc citrate dihydrate available in?
Zinc citrate dihydrate is available as a powder.

Technical content is compiled and updated by the SoleChem product team from public technical sources; the certificate of analysis (COA) governs product-specific specifications.

Other Names (Synonyms)

K72I3DEX9B|CITRATED ZINC|2-Hydroxy-1,2,3-propanetricarboxylic acid zinc salt|RefChem:6361|Trizinc dicitrate|1,2,3-Propanetricarboxylic acid, 2-hydroxy-, zinc salt (2:3)|Citric acid, zinc salt (2:3)

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What are the physical properties of Zinc citrate?

Color colorless powder
Odor Odorless
Form colorless powder
Water Solubility slightly soluble H2O; soluble dilute mineral acids and alkali hydroxides [MER06]
Log P -1.721 (est)

How is Zinc citrate classified and handled safely? Learn More

Warning
GHS07· Irritant GHS09· Environmental Hazard

Hazard Statements

H319 Causes serious eye irritation
H400 Very toxic to aquatic life
H410 Very toxic to aquatic life with long lasting effects
H411 Toxic to aquatic life with long lasting effects

Precautionary Statements

P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P391 Collect spillage.
P501 Dispose of contents/container in accordance with local regulations.
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