L-Malic acid-13C4

L-Malic acid-13C4 (CAS 150992-96-4) is a stable isotope-labeled form of L-malic acid in which all four carbon atoms are replaced with carbon-13. It is used primarily as an analytical reference standard and metabolic tracer.

This compound enables precise quantification and tracking of malic acid in complex biological and chemical matrices. In pharmaceutical and bioanalytical research, it serves as an internal standard for LC-MS/MS and GC-MS methods.

The use of this labeled standard improves accuracy when quantifying malic acid in drug formulations or biological fluids. Metabolic flux analysis in biotechnology relies on 13C-labeled organic acids to map carbon flow.

Researchers utilize this compound to track movement through the TCA cycle and related pathways. Food science researchers use it to authenticate natural malic acid content and detect adulteration in fruit-based products.

It is also applied in juices and acidulant systems to ensure product integrity. Isotope tracer studies in nutrition research apply this compound to investigate malic acid absorption and metabolism in vivo.

L-Malic acid-13C4 is supplied as a solid powder in research-scale quantities, typically ranging from milligrams to low-gram amounts. It is available at high isotopic purity, commonly ≥99 atom % 13C.

The chemical purity specifications are suited to reference standard applications. Packaging is designed for long-term stability under controlled storage conditions to maintain the integrity of the labeled material.