SoleChem

Sodium malate

Salts & Minerals Pharmaceuticals & Healthcare
CAS
676-46-0
EC
211-627-6
Mol. Weight
178.05 g/mol

Description

Sodium malate (CAS 676-46-0), also known by its food additive designation E350i, is the disodium salt of malic acid used commercially as a pH buffer and acidulant.

It delivers a mild, smooth tartness without the sharp acidity of mineral acids, making it a preferred choice in food and pharmaceutical formulations where precise pH control is required.

In food and beverage manufacturing, sodium malate regulates acidity in fruit-based products, confectionery, and soft drinks where a rounded, fruit-forward flavor profile is desired.

Pharmaceutical formulators use it as a buffering agent in oral liquid preparations and effervescent tablets to stabilize active ingredients across a defined pH range.

It functions as a flavor enhancer and acidity moderator in low-sodium seasoning blends and processed foods, where direct acidulants would be too aggressive.

In nutraceutical applications, it appears in mineral supplement formulations as a well-tolerated carrier salt. Sodium malate is supplied as a white crystalline powder or granules.

Food-grade material conforming to E350i specifications is the standard commercial form, with FCC-grade product available for applications requiring documented purity standards.

Pharmaceutical-grade supply meeting USP or Ph.Eur. specifications is available for regulated drug product manufacturing and high-purity industrial applications.

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Physical Properties

Melting Point >300°C (lit.)
Color White to Almost white
Odor at 100.00?%. odorless
Form Liquid
Log P -1.261 (est)

Safety & Handling (Learn More)

Warning GHS07
Hazard Statements
H315 Causes skin irritation
H319 Causes serious eye irritation
H335 May cause respiratory irritation
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P319 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P405 Store locked up.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P302+P352 IF ON SKIN: Wash with plenty of water.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P332+P317 Get emergency medical help.
P337+P317 If eye irritation persists: Get medical advice/attention. Get emergency medical help.
P362+P364 Take off contaminated clothing and wash it before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 2918 19 98
Storage Class 13 - Non Combustible Solids
WGK (Germany) 3

Documentation

Other Names

Malic acid, disodium salt|Disodium;2-hydroxybutanedioate|Disodium malate|E350i

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