Surfactants
REACH
Choleth-10
CAS Number
27321-96-6
What is Choleth-10?
Choleth-10 (CAS 27321-96-6) is an ethoxylated cholesterol derivative used as an emulsifier and humectant in cosmetic and pharmaceutical formulations. Also marketed as Cl-4494.
Where is Choleth-10 used?
- Topical cosmetics: stabilizes oil-in-water emulsions in creams, lotions and serums while supporting moisture retention
- Pharmaceuticals: solubilizes and disperses actives in ointments and dermal delivery systems
- Biotechnology: membrane-compatible surfactant in liposomal and lipid-based delivery systems
- Hair care: improves ingredient dispersion and deposit uniformity in conditioning treatments
- It enables stable emulsion formation in skin-contact products.
Good to know: Cosmetic-grade and pharmaceutical-grade specifications are available; grades ensure compliance across regulated and non-regulated markets.
Commercial specifications
- Packaging from small laboratory quantities to bulk industrial drums
Other Names (Synonyms)
(3beta)-cholest-5-en-3-ol, ethoxylated|2-(Cholest-5-en-3-yloxy)ethanol|Cl-4494|Poly(oxy-1,2-ethanediyl), α-(3β)-cholest-5-en-3-yl-ω-hydroxy-|Glycols, polyethylene, monocholesteryl ether|Cholesterol, monoether with polyethylene glycol|Cholestane, poly(oxy-1,2-ethanediyl) deriv.
How is Choleth-10 classified and handled safely? Learn More
Warning
GHS07· Irritant