Choleth-10
Description
Choleth-10 (CAS 27321-96-6) is an ethoxylated cholesterol derivative used as an emulsifier and humectant in cosmetic and pharmaceutical formulations. Recognized in trade under the designation Cl-4494, it bridges the gap between lipid-phase components and aqueous systems.
This chemical enables stable emulsion formation in skin-contact products. In topical cosmetic formulations, including creams, lotions, and serums, it stabilizes oil-in-water emulsions while supporting moisture retention at the skin surface.
Pharmaceutical formulators use it to solubilize and disperse active ingredients in semi-solid preparations such as ointments and dermal delivery systems. It is highly effective in maintaining the consistency of complex medicinal mixtures.
In biotechnology and life sciences, it functions as a membrane-compatible surfactant in liposomal and lipid-based delivery systems. Its cholesterol backbone supports bilayer integration, making it essential for advanced research applications.
Hair care products, particularly conditioning treatments, incorporate it to improve ingredient dispersion and deposit uniformity on the hair shaft. This ensures that active conditioning agents are distributed evenly across the surface.
The material is supplied as a waxy solid or viscous paste depending on temperature and processing conditions. It is available in cosmetic-grade and pharmaceutical-grade specifications to meet various formulator requirements.
These grades ensure compliance across regulated and non-regulated markets globally. Packaging typically ranges from small laboratory quantities to bulk industrial drums for commercial-scale production and manufacturing needs.
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Documentation
Other Names
(3beta)-cholest-5-en-3-ol, ethoxylated|2-(Cholest-5-en-3-yloxy)ethanol|Cl-4494|Poly(oxy-1,2-ethanediyl), α-(3β)-cholest-5-en-3-yl-ω-hydroxy-|Glycols, polyethylene, monocholesteryl ether|Cholesterol, monoether with polyethylene glycol|Cholestane, poly(oxy-1,2-ethanediyl) deriv.
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