Denatonium benzoate

Denatonium benzoate (CAS 3734-33-6), also known commercially as Bitrex, is recognized as the most intensely bitter substance known. It is used industrially as an aversive agent to prevent accidental ingestion of hazardous or non-consumable products. At concentrations as low as a few parts per million, it renders products unpalatable without affecting their functional performance. In pharmaceuticals and healthcare, it is added to topical formulations and rubbing alcohols.

These applications discourage oral ingestion of products not intended for consumption. Personal care manufacturers incorporate it into nail-biting deterrent products and hand sanitizers where accidental ingestion is a safety concern. Industrial formulators use it to denature ethanol and other solvents, satisfying regulatory requirements for denatured alcohol without altering solvent performance. It also appears in household and consumer product formulations.

Common applications include antifreeze, detergents, and cleaning agents to protect children and animals from accidental poisoning. Denatonium benzoate anhydrous is the standard commercial form, supplied as a white crystalline powder. It is available in pharmaceutical-grade specifications meeting USP and BP standards, as well as technical grade for industrial denaturation applications. Typical supply quantities range from small packs to bulk quantities.

These bulk quantities are suited for large-scale formulation or blending operations. The material remains stable under standard storage conditions and provides a cost-effective solution for safety compliance in various industries.