SoleChem

Denatonium benzoate

Salts & Minerals Pharmaceuticals & Healthcare
CAS
3734-33-6
EC
223-095-2
Mol. Weight
446.6 g/mol

Description

Denatonium benzoate (CAS 3734-33-6), also known commercially as Bitrex, is recognized as the most intensely bitter substance known. It is used industrially as an aversive agent to prevent accidental ingestion of hazardous or non-consumable products.

At concentrations as low as a few parts per million, it renders products unpalatable without affecting their functional performance. In pharmaceuticals and healthcare, it is added to topical formulations and rubbing alcohols.

These applications discourage oral ingestion of products not intended for consumption. Personal care manufacturers incorporate it into nail-biting deterrent products and hand sanitizers where accidental ingestion is a safety concern.

Industrial formulators use it to denature ethanol and other solvents, satisfying regulatory requirements for denatured alcohol without altering solvent performance. It also appears in household and consumer product formulations.

Common applications include antifreeze, detergents, and cleaning agents to protect children and animals from accidental poisoning. Denatonium benzoate anhydrous is the standard commercial form, supplied as a white crystalline powder.

It is available in pharmaceutical-grade specifications meeting USP and BP standards, as well as technical grade for industrial denaturation applications. Typical supply quantities range from small packs to bulk quantities.

These bulk quantities are suited for large-scale formulation or blending operations. The material remains stable under standard storage conditions and provides a cost-effective solution for safety compliance in various industries.

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Physical Properties

Melting Point 168 °C
Boiling Point 555.91°C (rough estimate)
Density 1.1256 (rough estimate)
Flash Point 100°C
Appearance white crystals
Color White to Off-White
Odor at 100.00?%. bland
Form Solid
Water Solubility 42.555g/L at 25℃
Vapor Pressure 0Pa at 25℃
Refractive Index 1.5800 (estimate)
Log P 2.2 at 25℃

Safety & Handling (Learn More)

Danger GHS05 GHS07
Hazard Statements
H302 Harmful if swallowed
H318 Causes serious eye damage
H332 Harmful if inhaled
H412 Harmful to aquatic life with long lasting effects
H302+H332 Harmful if swallowed or if inhaled
Precautionary Statements
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P317 Get emergency medical help.
P330 Rinse mouth.
P501 Dispose of contents/container in accordance with local regulations.
P264+P265 Wash … thoroughly after handling.
P301+P317 Get emergency medical help.
P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
P305+P354+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Trade & Regulatory

HS Code 29242995
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 2

Documentation

Other Names

denatonium benzoate anhydrous|Bitrex|Lidocaine benzyl benzoate|Aversion|THS-839|Anispray|Gori|Benzoato de denatonio

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