Isophorone diisocyanate

CAS Number
4098-71-9
EC Number
223-861-6
Abbreviation
IPDI

What is Isophorone diisocyanate?

Isophorone diisocyanate (CAS 4098-71-9), commonly known as IPDI, is an aliphatic cycloaliphatic diisocyanate monomer used to build polyurethane polymers with superior UV and weathering resistance.

Where is Isophorone diisocyanate used?

  • Automotive and industrial coatings: two-component polyurethane topcoats and clearcoats that resist yellowing under prolonged UV exposure
  • Aerospace and defense: protective coatings on aircraft exteriors and structural components
  • Adhesives and sealants: crosslinker for moisture-cure or two-part systems bonding plastics, composites, and metals
  • It also serves as a building block for dispersions.

Good to know: Unlike aromatic isocyanates, IPDI-based systems retain color stability over time. Prepolymer and trimer forms are also commercially available for formulators requiring modified reactivity or reduced vapor pressure.

Commercial specifications

  • Purity specifications are typically at 99%+ for polymer-grade applications.
  • Clear to slightly yellow liquid in standard industrial packaging including drums and IBC containers.

Other Names (Synonyms)

Isophorone diamine diisocyanate|Isocyanic acid, methylene(3,5,5-trimethyl-3,1-cyclohexylene) ester|3-Isocyanatomethyl-3,5,5-trimethylcyclohexylisocyanate|IPDI|5-Isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane|Cyclohexane, 5-isocyanato-1-(isocyanatomethyl)-1,3,3-trimethyl-|3,3,5-Trimethyl-5-(isocyanatomethyl)cyclohexyl isocyanate|1-(Isocyanatomethyl)-5-isocyanato-1,3,3-trimethylcyclohexane

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What are the physical properties of Isophorone diisocyanate?

Melting Point -60 °C
Boiling Point 158 °C @ Press: 10 Torr
Density 1.056 g/cm³
Flash Point >230 °F
Appearance colourless or slightly yellow liquid
Color Clear colorless to slightly yellow
Form Liquid
Water Solubility <0.1 g/100 mL at 25 ºC
Vapor Pressure 0.0004 hPa (20 °C)
Refractive Index n 20/D 1.484(lit.)
Log P 4.75 at 25℃

How is Isophorone diisocyanate classified and handled safely? Learn More

Danger
GHS06· Toxic GHS08· Health Hazard GHS09· Environmental Hazard GHS07· Irritant GHS05· Corrosive

Hazard Statements

H302 Harmful if swallowed
H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H315 Causes skin irritation

Precautionary Statements

P233 Keep container tightly closed.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.

Which trade and regulatory codes apply to Isophorone diisocyanate?

HS Code 29291090
UN Number 2290
ADR Class 6.1
Packing Group III
Storage Class 6.1A - Combustible, acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 2
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