Isophthaloyl chloride

CAS Number
99-63-8
EC Number
202-774-7
Abbreviation
IPC

What is Isophthaloyl chloride?

Isophthaloyl chloride (CAS 99-63-8), also known as IPC or m-phthaloyl chloride, is a reactive diacid chloride monomer used to build high-performance polymer chains through acylation reactions.

Where is Isophthaloyl chloride used?

  • Aramids, polyamides and polyesters: building block where thermal stability and mechanical strength are end targets
  • Aramid fiber production: reacts with aromatic diamines to form meta-aramid polymers, basis of heat-resistant textiles for protective apparel and industrial filtration
  • Polyamide and polyester resins: introduces isophthalate units that improve flexibility and chemical resistance
  • Coatings and adhesives: cross-linking agent that builds dense polymer networks for high-temperature or chemically aggressive service
  • Pharmaceutical synthesis: acylating intermediate for active ingredients and specialty amide-bond-containing compounds

Commercial specifications

  • Standard commercial grades for industrial and synthesis-scale applications
  • High-purity grades for pharmaceutical and fine chemical manufacturing
  • Packaging from small laboratory quantities to bulk volumes for polymer production

Other Names (Synonyms)

Isophthaloyl dichloride|1,3-Benzenedicarbonyl dichloride|m-Phthaloyl chloride|Isophthalic acid chloride|m-Phthalic dichloride|1,3-BENZENEDICARBONYL CHLORIDE|Isophthalic acid dichloride|Isophthalic chloride|IPC

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What are the physical properties of Isophthaloyl chloride?

Melting Point 43-44 °C
Boiling Point 276 °C
Density 1.3880 g/cm³ @ Temp: 17 °C
Flash Point 356 °F
Appearance white crystalline mass
Color White
Form Crystalline Mass
Water Solubility reacts
Vapor Pressure 0.03 mm Hg ( 25 °C)
Refractive Index 1.5700 (estimate)

How is Isophthaloyl chloride classified and handled safely? Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS07· Irritant

Hazard Statements

H312 Harmful in contact with skin
H314 Causes severe skin burns and eye damage
H318 Causes serious eye damage
H331 Toxic if inhaled

Precautionary Statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.

Which trade and regulatory codes apply to Isophthaloyl chloride?

HS Code 29173940
UN Number 3261
ADR Class 8
Packing Group II
Storage Class 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials
WGK (Germany) 1
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