Tetrakis(hydroxymethyl)phosphonium sulfate

CAS Number
55566-30-8
EC Number
259-709-0
Chemical Formula
C4H12O4P.1/2O4S
Molecular Weight
406.28 g/mol
Abbreviation
THPS

Description

Tetrakis(hydroxymethyl)phosphonium sulfate (CAS 55566-30-8), commonly known as THPS, is a water-soluble organophosphorus biocide and flame retardant used across industrial and specialty chemical markets. Supplied under trade names such as Retardol S and Pyroset TKO, it delivers broad-spectrum antimicrobial activity alongside durable flame retardancy in treated substrates for various sectors.

In water treatment, THPS controls sulfate-reducing bacteria and biofilm formation in oilfield injection systems, cooling towers, and industrial process water systems to maintain operational efficiency. Textile and nonwoven manufacturers apply it as a durable flame retardant finish for cotton and cellulosic fabrics, where it bonds to fiber during curing to meet fire performance standards.

In leather processing, it functions as a biocide during hide preservation and wet-end operations to prevent microbial degradation. This ensures the quality and longevity of the leather materials. Personal care and cosmetic formulators incorporate it at low concentrations as a preservative active against a broad range of bacteria and fungi, ensuring product safety and shelf stability.

THPS is commercially available as an aqueous solution, typically at 75% active content. It is supplied in technical grade for industrial water treatment and textile applications. Select grades meet specifications for cosmetic preservation use. Packaging options generally include drums and intermediate bulk containers (IBCs) to suit varying procurement volumes and logistics.

Other Names (Synonyms)

Retardol S|Pyroset TKO|Octakis(hydroxymethyl)phosphonium sulfate|NCI-C55050|Phosphonium, tetrakis(hydroxymethyl)-, sulfate (2:1) (salt)|Phosphonium, tetrakis(hydroxymethyl)-, sulfate (2:1)|THPS

Key Technical Features

  • High Purity Grade standard
  • Consistent Batch Quality
  • Full Regulatory & REACH Support
  • Global Logistics Network enabled

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Physical Properties

Melting Point -35°C
Boiling Point 111°C
Density 1.41 g/cm³ @ Temp: 20 °C
Flash Point 96 °C
Color Colorless to Almost colorless
Form liquid
Water Solubility >=10 g/100 mL at 18 ºC
Vapor Pressure 0Pa at 20℃
Log P -9.8

Documentation

Safety & Handling Learn More

Danger
GHS05· Corrosive GHS06· Toxic GHS07· Irritant GHS08· Health Hazard GHS09· Environmental Hazard

Hazard Statements

H301 Toxic if swallowed
H302 Harmful if swallowed
H317 May cause an allergic skin reaction
H318 Causes serious eye damage

Precautionary Statements

P203 Obtain, consult and follow expert instructions for use.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash … thoroughly after handling.

Trade & Regulatory

HS Code 29319019
UN Number 2922
ADR Class 8
Packing Group III
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 1
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