Sclareolide

Sclareolide (CAS 564-20-5), also known as 12-Norambreinolide and carrying FEMA No. 3794, is a naturally derived lactone obtained primarily from clary sage. It functions as a fragrance fixative and flavor modifier. It serves as a synthetic intermediate in the production of high-value aroma chemicals and ambergris-type compounds. In fragrance formulation, sclareolide anchors volatile top notes and extends the longevity of fine fragrance products.

This includes applications in perfumes, body lotions, and hair care lines. It is a key precursor in the synthesis of ambroxide and related ambergris-type odorants, making it commercially significant for specialty aroma chemical manufacturers. As a FEMA 3794-approved flavoring agent, it is used in food and beverage applications where subtle musky or woody nuances are required. In polymer and resin systems, its lactone structure supports cross-linking applications.

This positions the material as a building block for specialty monomers and curing agents. Sclareolide is supplied as a white to off-white crystalline powder for industrial and commercial use. Standard commercial grades include technical and fragrance-grade material, with purity levels typically ranging from 95% to 98%+. Food and flavor applications are supplied in compliance with FEMA-recognized specifications.