Flavors & Fragrances
REACH
Sclareolide
CAS Number
564-20-5
EC Number
209-269-0
FEMA Number
FEMA 3794
What is Sclareolide?
Sclareolide (CAS 564-20-5) is a naturally derived lactone obtained primarily from clary sage. Also known as 12-Norambreinolide; FEMA No. 3794.
Where is Sclareolide used?
- Fragrance fixative that anchors volatile top notes and extends longevity in perfumes, body lotions and hair care
- Aroma chemical synthesis: intermediate for high-value aroma chemicals and key precursor to ambroxide and related ambergris-type odorants
- Polymers and resins: lactone structure supports cross-linking, and the material serves as a building block for specialty monomers and curing agents
- As a FEMA 3794-approved flavor modifier, it adds subtle musky or woody nuances to food and beverages.
Good to know: Food and flavor use follows FEMA-recognized specifications.
Commercial specifications
- Purity typically 95% to 98%+
Other Names (Synonyms)
12-Norambreinolide|37W4O0O6E6|RefChem:884697|(3aR)-(+)-Sclareolide|(3aR,5aS,9aS,9bR)-Decahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan-2(1H)-one|SYMBRIGHT 2036
What are the physical properties of Sclareolide?
Melting Point 123.2-124.3 °C
Boiling Point 321.4±10.0 °C(Predicted)
Density 1.009±0.06 g/cm3(Predicted)
Color White to Off-White
Odor at 10.00 % in isopropyl myristate. dry paper woody ambergris labdanum
Form neat
Water Solubility 10mg/L at 25℃
Vapor Pressure 0Pa at 25℃
Log P 4.5 at 25℃
Which trade and regulatory codes apply to Sclareolide?
HS Code 29322090
Storage Class 11 - Combustible Solids
WGK (Germany) 2