Safrole

Safrole (CAS 94-59-7), also known as shikimole, is a naturally occurring phenylpropanoid compound isolated primarily from sassafras root bark oil and certain other essential oils. Historically, it served as a key flavoring and fragrance ingredient before regulatory restrictions limited its direct use in food and cosmetic applications across various global markets.

In pharmaceutical and chemical synthesis, it functions as a precursor in the production of piperonyl butoxide, a synergist used in insecticide formulations, making it a controlled intermediate. Fragrance manufacturers have historically used it as a starting material for heliotropin (piperonal), a widely recognized floral fragrance compound used in high-end perfumery and soaps.

In research and analytical contexts, it is sourced as a reference standard for quality control testing of essential oils and botanical extracts to ensure product safety and purity. Regulatory monitoring laboratories also procure it as a certified reference material for compliance testing in food and cosmetic matrices to meet international safety requirements.

The product is available as a liquid, typically supplied in small quantities suited to research, reference standard, and controlled industrial uses under strict regulatory frameworks. Buyers should confirm applicable import and handling permits before procurement. Supply is generally offered at high-purity analytical grades appropriate for laboratory and reference applications.