Safrole

Safrole (CAS 94-59-7), also known as shikimole, is a naturally occurring phenylpropanoid compound isolated primarily from sassafras root bark oil and certain other essential oils.

Where is Safrole used?

• Pharmaceutical and chemical synthesis: precursor in the production of piperonyl butoxide, a synergist used in insecticide formulations
• Fragrance: starting material for heliotropin (piperonal), a floral fragrance compound used in high-end perfumery and soaps
• Research and analytical: reference standard for quality control testing of essential oils and botanical extracts
• Regulatory monitoring laboratories procure it as a certified reference material for compliance testing in food and cosmetic matrices.

Good to know: Historically used as a flavoring and fragrance ingredient before regulatory restrictions limited its direct use in food and cosmetic applications. Buyers should confirm applicable import and handling permits before procurement.

Commercial specifications

• High-purity analytical grades appropriate for laboratory and reference applications