Ascaridole

CAS Number
512-85-6
EC Number
208-147-4

What is Ascaridole?

Ascaridole (CAS 512-85-6) is a naturally occurring bicyclic monoterpene endoperoxide isolated primarily from chenopodium oil, where it constitutes the majority of the active fraction.

Where is Ascaridole used?

  • Pharmaceutical and agrochemical research: synthetic intermediate
  • Pharmaceutical development: starting material or structural reference for novel antiparasitic and antimicrobial candidates, particularly where endoperoxide pharmacophores are under investigation
  • Agrochemical research: biocidal active in formulations targeting soil-borne pathogens and certain pest species
  • Oxidative chemistry studies: model compound for developing new crop protection actives
  • Academic and industrial laboratories: natural product synthesis
  • It is frequently used for comparative bioactivity screening.

Good to know: Historically significant as one of the first natural compounds with confirmed antiparasitic activity, it serves as a reference compound. Certificate of Analysis documentation with purity confirmation by GC or HPLC is standard for procurement at research and pharmaceutical grades.

Commercial specifications

  • Liquid, typically at high purity grades suited to research and pharmaceutical intermediate applications
  • Small to moderate quantities through specialty fine chemical and reference standard suppliers

Other Names (Synonyms)

1,4-peroxy-p-menth-2-ene|1,4-peroxido-p-menthene-2|1,4-epidioxy-p-menth-2-ene|1-methyl-4-(1-methylethyl)-2,3-dioxabicyclo[2.2.2]oct-5-ene|1-isopropyl-4-methyl-2,3-dioxabicyclo[2.2.2]oct-5-ene|Ascaridol|Ascaricum|Ascarisin

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What are the physical properties of Ascaridole?

Melting Point 3.3 °C
Boiling Point 39-40 °C @ Press: 0.2 Torr
Density 1.0115 g/cm³ @ Temp: 20 °C
Flash Point 55.9±28.6°C
Color Colorless unstable liquid
Form Liquid
Refractive Index 1.4769 (589.3 nm, 25℃)
Log P 2.244 (est)
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