Triheptanoin
Description
Triheptanoin (CAS 620-67-7), also known as glycerol triheptanoate, is a synthetic triglyceride composed of three heptanoic acid chains esterified to a glycerol backbone. It functions as an emollient, skin-conditioning agent, and carrier in formulations where controlled lipid delivery and oxidative stability are priorities.
In cosmetic and personal care formulations, it provides a lightweight, non-greasy skin feel in serums, sunscreens, and color cosmetics. It also acts as a solvent for UV filters and oil-soluble actives, offering a high-performance alternative to conventional plant-derived oils.
Pharmaceutical manufacturers use it as a carrier oil in topical drug delivery systems and as a medium-chain triglyceride alternative in oral and parenteral nutrition research applications. Its unique structure allows for precise metabolic targeting in clinical settings.
In food and nutraceutical contexts, it serves as a structured lipid for metabolic studies and specialized clinical nutrition products. Its oxidative stability relative to unsaturated oils makes it a preferred carrier in sensitive formulations with long shelf-life requirements.
The material is supplied as a clear, colorless to pale yellow liquid. It is available in cosmetic-grade and pharmaceutical-grade specifications, with pharmaceutical supply typically aligned to GMP manufacturing standards.
Packaging ranges from small quantities for R&D use to bulk drums for commercial production. This versatility ensures that both laboratory-scale development and large-scale industrial manufacturing needs are met with consistent quality and reliable supply chains.
Physical Properties
| Boiling Point | 200 °C @ Press: 1 Torr |
| Density | 0.9665 g/cm³ @ Temp: 20 °C |
| Appearance | colourless liquid |
| Color | Colorless to light yellow |
| Form | A liquid |
| Refractive Index | n 20/D 1.444 |
| Log P | 8.86 at 22℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 1 |
Documentation
Other Names
Glycerol triheptanoate|Triheptanoic glyceride|Heptanoin, tri-|Dermofeel TC 7|GLYCERYL TRIHEPTANOATE|Heptanoic acid, 1,1′,1′′-(1,2,3-propanetriyl) ester|Heptanoic acid, 1,2,3-propanetriyl ester
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