Liquid nitrogen

CAS Number
7727-37-9
EC Number
231-783-9
E Number
E939

What is Liquid nitrogen?

Liquid nitrogen (CAS 7727-37-9), a cryogenic gas regulated as E941 in food applications, is produced by fractional distillation of air.

Where is Liquid nitrogen used?

  • Industrial: ultra-low-temperature refrigerant and inert blanketing agent
  • Food processing: cryogenic tunnel freezing of meat, seafood, and baked goods
  • Pharmaceutical and biotech: cryopreservation of cell lines, biological samples, and vaccines
  • Electronics and semiconductors: purging process chambers, cooling components during precision machining, and maintaining inert atmospheres during sensitive fabrication steps
  • Beverage and packaging lines: injected into containers before sealing to displace oxygen and extend shelf life
  • It is essential for API intermediates requiring storage below −150°C.

Good to know: Food-grade supply conforming to E941 specifications and industrial-grade product are the standard commercial distinctions.

Commercial specifications

  • Purity levels typically range from 99.998% for high-purity applications to standard industrial grades
  • Bulk dewars, ISO tanks, and cryogenic cylinders, with delivery formats scaled to site volumes
  • On-site generation systems for high-volume users

Other Names (Synonyms)

LN₂|LN2|nitrogen gas|diazyne|gaseous signaling molecule|gasocrine signal|nitrogen|Molecular nitrogen|E941

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What are the physical properties of Liquid nitrogen?

Melting Point -210.01 °C
Boiling Point -195.79 °C
Density 4.604 x 10⁻³ g/cm³ (vapor) @ Temp: -195.8 °C
Appearance Nitrogen is a nonflammable, stable, odorless, cryogenic liquid or a compressed gas.
Color colorless
Odor odorless, tasteless
Form colorless gas
Water Solubility slightly soluble H2O; insoluble alcohol [HAW93]

How is Liquid nitrogen classified and handled safely? Learn More

Warning
GHS04· Compressed Gas GHS08· Health Hazard

Hazard Statements

H280 Contains gas under pressure; may explode if heated [Warning Gases under pressure]
H304 May be fatal if swallowed and enters airways [Danger Aspiration hazard]
H401 Toxic to aquatic life [Hazardous to the aquatic environment, acute hazard]

Which trade and regulatory codes apply to Liquid nitrogen?

UN Number 1066
ADR Class 2.2
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