Diazolidinyl urea
Description
Diazolidinyl urea (CAS 78491-02-8), also known commercially as Germall 11, is a formaldehyde-releasing preservative used across personal care and pharmaceutical formulations.
It provides broad-spectrum antimicrobial protection against bacteria, yeast, and mold, extending the shelf life of water-containing products in various industrial applications.
In rinse-off and leave-on cosmetics, including lotions, shampoos, and conditioners, it is used at low concentrations to prevent microbial contamination throughout the product lifecycle.
Liquid and gel-based personal care formulations benefit from its water solubility, allowing straightforward incorporation without disrupting the stability of the emulsion system.
Pharmaceutical topical preparations such as creams and ointments rely on it to meet preservation efficacy requirements under standard challenge testing protocols for safety.
It is frequently paired with parabens or other co-preservatives to achieve broader coverage and reduce the required use level of each individual ingredient in the final blend.
Diazolidinyl urea is supplied as a white to off-white powder. It is available in cosmetic-grade and pharmaceutical-grade specifications, conforming to USP and BP monographs.
Standard packaging ranges from kilogram quantities for formulators to bulk drum supply for larger manufacturing operations, ensuring consistent quality for all industrial clients.
Physical Properties
| Boiling Point | 421.04°C (rough estimate) |
| Density | 1.4734 (rough estimate) |
| Appearance | white powder |
| Color | White to Off-White |
| Form | Solid |
| Water Solubility | 1000g/L at 20℃ |
| Vapor Pressure | 0Pa at 20℃ |
| Refractive Index | 1.6590 (estimate) |
| Log P | 0.9 at 20℃ |
Safety & Handling (Learn More)
Trade & Regulatory
| HS Code | 29339900 |
| WGK (Germany) | 2 |
Documentation
Other Names
N,N'-Bis(hydroxymethyl) urea|Germall 11|Imidazolidinyl urea 11|N9VX1IBW6K|H5RIZ3MPW4|Germall II|Germaben II-E
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